1. (v. t. & i.) To gather into small folds or wrinkles; to contract into ridges and furrows; to corrugate; -- often with up; as, to pucker up the mouth.

2. (n.) A fold; a wrinkle; a collection of folds.

3. (n.) A state of perplexity or anxiety; confusion; bother; agitation.

abbreviate agitation all-overs angst anxiety anxiety hysteria anxiety neurosis anxious bench anxious concern anxious seat anxiousness apprehension apprehensiveness befuddlement bewilderment bother botheration cankerworm of care care chaos circumscribe cloud coarct cocker cockle compact compress concentrate concern concernment condense confusion consolidate constrict constringe contract corrugate corrugation cramp crankle crease crimp crimple crinkle crinkling crumple curtail daze decrease discombobulation discomfiture discomposure disconcertion disorder disorganization disorientation disquiet disquietude distress disturbance dither draw draw in draw together dread embarrassment fear flap flummox flurry fluster flusteration flustration flutter fog fold foofaraw foreboding forebodingness frenzy fret fuddle fuddlement furrow fuss gather haze inquietude jumble knit knot lather malaise maze mess misgiving mist muddle muddlement narrow nervous strain nervous tension nervousness overanxiety perplexity perturbation pins and needles pleat pother pucker up purse reduce ridge rimple ripple rivel ruche ruck ruckle ruffle rumple screw up shirr shirring shorten shuffle solicitude solidify squeeze stew strain strangle strangulate suspense sweat swivet tension tighten tizzy trouble tuck twitter twitteration uneasiness unquietness unsettlement upset vexation wimple wrinkle wrinkling zeal