1. (n.) The quality or state of being uneasy; restlessness; disquietude; anxiety.

2. (n.) The quality of making uneasy; discomfort; as, the uneasiness of the road.

Faustianism abashment agitation all-overs angst anguish anxiety anxiety hysteria anxiety neurosis anxious bench anxious concern anxious seat anxiousness apprehension apprehensiveness attack of nerves boredom breathless impatience buck fever cankerworm of care care case of nerves chafing cheerlessness chills of fear cold comfort cold creeps cold shivers cold sweat concern concernment confusion creeps disappointment discomfiture discomfort discomposure disconcertion disconcertment discontent discontentedness discontentment disgruntlement dislike displeasure disquiet disquietude dissatisfaction dissatisfiedness distress disturbance divine discontent dread dullness eagerness emptiness ennui envy excessive irritability excitement existential woe fear fear and trembling fidgetiness fidgets flatness foreboding forebodingness fretfulness fretting goose bumps gooseflesh grimness haste heartquake horripilation ill humor impatience impatientness impetuousness inquietude jimjams joylessness lack of pleasure lather malaise misgiving morbid excitability nausea nerves nervosity nervous stomach nervous strain nervous tension nervousness nongratification nonsatisfaction overanxiety painfulness palpitation panic panickiness peevishness perturbation petulance pins and needles pucker quaking querulousness quiver of terror rebelliousness resentment restiveness restlessness savorlessness shivers solicitude sourness spell of nerves spleen stage fright staleness state of nerves stew strain sulkiness suspense sweat tastelessness tediousness tedium tense readiness tension thrill of fear tic trepidation trepidity trouble twitching uncomfortableness unease unfulfillment unhappiness unpatientness unpleasure unquietness unsatisfaction upset vellication vexation vexation of spirit worry zeal