(n.) Disturbed state; uneasiness either of body or mind; restlessness; disquietude.

agitation ailment all-overs angst anguish anxiety anxiety hysteria anxiety neurosis anxious bench anxious concern anxious seat anxiousness apprehension apprehensiveness bluster bobbery boil boiling boredom brouhaha bustle cankerworm of care care cheerlessness chills of fear churn cold creeps cold shivers cold sweat commotion concern concernment conturbation creeps didder discomfort discomposure discontent dislike disorder displeasure disquiet disquietude dissatisfaction distress disturbance dithers dread dullness ebullition embroilment emptiness ennui excitement existential woe fear fear and trembling ferment fermentation fever feverishness fidgetiness fidgets flap flatness flurry fluster flutter flutteration foment foreboding forebodingness fume fuss goose bumps gooseflesh grimness heartquake heaving horripilation hubbub hurly-burly jimjams jitters joylessness jumpiness lack of pleasure maelstrom malaise misgiving moil nausea nerviness nervosity nervous strain nervous tension nervousness nongratification nonsatisfaction overanxiety painfulness palpitation panting perturbation pins and needles pitapat pitter-patter pucker quaking quaver quavering quiver quiver of terror quivering restiveness restlessness roil rout row savorlessness seethe seething shakes shaking shiver shivers shudder solicitude spleen staleness stew stir strain suspense sweat swirl tastelessness tediousness tedium tension thrill of fear throb throbbing to-do tremble trembling tremor trepidation trepidity trouble tumult tumultuation turbidity turbulence turmoil twitter uncomfortableness unease uneasiness unhappiness unpleasure unquietness unrest unsatisfaction upset vexation vexation of spirit zeal