1. (v. t.) To deprive of peace, rest, or tranquility; to make uneasy or restless; to disturb\.

2. (a.) Deprived of quiet; impatient; restless; uneasy.

3. (n.) Want of quiet; want of tranquility in body or mind; uneasiness; restlessness; disturbance; anxiety.

afflict affright agitate agitation ailment alarm all-overs angst anguish anxiety anxiety hysteria anxiety neurosis anxious bench anxious concern anxious seat anxiousness apprehension apprehensiveness be tedious beat beat up bluster bobbery boil boiling bore boredom bother brouhaha burden bustle cankerworm of care care cheerlessness chills of fear churn churn up cold creeps cold shivers cold sweat commotion concern concernment conturbation convulse creeps curdle the blood didder disarrange discombobulate discomfort discompose discomposure disconcert discontent dislike disorder displeasure disquietude dissatisfaction distress disturb disturbance dithers dread dullness ebullition electrify embroilment emptiness ennui excite excitement existential woe fear fear and trembling ferment fermentation fever feverishness fidgetiness fidgets flap flatness flurry fluster flutter flutteration foment foreboding forebodingness frazzle fret fright frighten fume funk fuss give concern goose bumps gooseflesh grimness heartquake heaving horripilate horripilation hubbub hurly-burly inquietude jar jimjams jitters jolt joylessness jumpiness lack of pleasure leave unsatisfied load with care maelstrom make one tremble malaise misgiving moil nausea nerviness nervosity nervous strain nervous tension nervousness nongratification nonsatisfaction overanxiety paddle painfulness palpitation panting perturb perturbate perturbation pins and needles pitapat pitter-patter pucker put to it quaking quaver quavering quiver quiver of terror quivering raise apprehensions rattle restiveness restlessness rile ripple rock roil roughen rout row ruffle rumple savorlessness scare seethe seething shake shake up shakes shaking shiver shivers shock shudder solicitude spleen spook stagger staleness startle stew stir stir up strain suspense sweat swirl tastelessness tediousness tedium tension thrill of fear throb throbbing to-do tremble trembling tremor trepidation trepidity trouble tumult tumultuation turbidity turbulence turmoil twitter uncomfortableness unease uneasiness unhappiness unhinge unman unnerve unpleasure unquietness unrest unsatisfaction unsettle unstring untune upset vexation vexation of spirit whip whip up whisk work up worry zeal