(n.) Want of ease; uneasiness.

agitation all-overs anguish anxiety anxiety hysteria anxiety neurosis anxious bench anxious concern anxious seat anxiousness apprehension apprehensiveness boredom cankerworm of care care cheerlessness concern concernment discomfort discomposure discontent dislike displeasure disquiet disquietude dissatisfaction distress disturbance dread dullness emptiness ennui existential woe fear flatness foreboding forebodingness grimness inquietude joylessness lack of pleasure malaise misgiving nausea nervous strain nervous tension nervousness nongratification nonsatisfaction overanxiety painfulness perturbation pins and needles pucker savorlessness solicitude spleen staleness stew strain suspense tastelessness tediousness tedium tension trouble uncomfortableness unease uneasiness unhappiness unpleasure unquietness unsatisfaction upset vexation vexation of spirit zeal