(v. t.) To deprive of inhabitants; to depopulate.

abandoned acarpous acheronian afflict aggrieve agonize alone anguish annihilate arid bare barren black bleak break down bring to ruin bring to tears celibate cheerless childless comfortless condemn confound consume crush crushed cut up damn dark daunt deal destruction decimate deep-troubled defenseless deject dejected demolish depopulate depredate depress depressed desecrate desert deserted desole despoil despondent destitute destroy destroyed devastate devastated devour disconsolate discourage discouraged dishearten dismal dismay dispeople dispirit dispirited dissolve distressed down downcast downhearted drained draw tears drear dreary dried-up dry embitter empty engorge excruciate exhausted fallow fatherless forlorn forsaken friendless fruitless funereal gaunt gelded gloomy gobble gobble up godforsaken grieve gut gut with fire havoc heart-stricken heart-struck heartsick heartsore helpless homeless hopeless impotent incinerate inconsolable ineffectual infecund infertile inundate isolated issueless jejune joyless kithless lay in ruins lay waste leached lonely low-spirited melancholy menopausal miserable motherless mournful murky neglected nonfertile nonproducing nonproductive nonprolific obliterate oppress outcast overwhelm pillage poor poverty-stricken prostrate ravage ravaged raze remote ruin ruinate ruined sack sad sadden shipwreck sick sick at heart sine prole solitary somber sorrow sorrowful soul-sick spiritless spoliate sterile stricken sucked dry suicidal swallow up teemless throw into disorder torment torture unconsolable uncouth uncultivated unfertile unfrequented unfriended unfruitful unhappy uninhabited unleash destruction unleash the hurricane unoccupied unpeople unplowed unproductive unprolific unsown untilled upheave vacant vandalize vaporize virgin waste wasted without issue woebegone woeful wrack wreak havoc wreck wretched