1. (v. i.) To writhe with agony; to suffer violent anguish.

2. (v. i.) To struggle; to wrestle; to strive desperately.

3. (v. t.) To cause to suffer agony; to subject to extreme pain; to torture.

ache afflict agonize over ail anguish battle be at sea be uncertain bear beat about bite blanch bleed blench bloody brood over buffet burn chafe claw contend convulse crucify cut desolate distress doubt endure excruciate feel pain feel the pangs feel unsure fester fight flounder fret gall give pain gnaw go hard with grate grieve grimace grind gripe grope grunt and sweat harrow hassle have a misery huff and puff hurt impale inflame inflict pain irritate kill by inches lacerate lancinate macerate martyr martyrize mope mourn nip pain pierce pinch pine pine away pound prick prolong the agony punish put to torture puzzle over question rack rankle rasp rip rub savage scarify scuffle shoot shrink smart sorrow squirm stab sting strive struggle suffer suffer anguish take on thrash about thrill throb tingle torment torture toss trouble try tussle tweak twinge twist twitch wince wonder wonder whether wound wrestle wring writhe