(v. t.) To impair the strength of; to weaken; to enfeeble; as, to debilitate the body by intemperance.

abate afflict attenuate beat blunt bugger burn out cramp cripple damp dampen de-energize deaden derange devitalize disable disenable disorder do in do up drain dull enervate enfeeble eviscerate exhaust extenuate fag fag out fatigue flag frazzle gruel hamstring harass hors de combat hospitalize hurt inactivate incapacitate indispose invalid jade kibosh knock out knock up lame lay low lay up maim mar mitigate overfatigue overstrain overtire overweary poop poop out prostrate put queer queer the works rattle reduce sabotage sap shake shake up sicken soften up spike spoil tire tire out tire to death tucker unbrace undermine unfit unman unnerve unstrengthen unstring use up weaken wear wear down wear on wear out weary wilt wind wing wreck