1. (n.) Weariness from bodily labor or mental exertion; lassitude or exhaustion of strength.

2. (n.) The cause of weariness; labor; toil; as, the fatigues of war.

3. (n.) The weakening of a metal when subjected to repeated vibrations or strains.

4. (n.) To weary with labor or any bodily or mental exertion; to harass with toil; to exhaust the strength or endurance of; to tire.

abatement abscess acedia adynamia ague anemia ankylosis annoy anoxia apathy apnea asphyxiation asthma ataxia atony atrophy attenuation attrition backache be infinitely repetitive be tedious beat blah feeling bleeding blennorhea bloodlessness blow blunting boredom bother break down burn out cachexia cachexy chill chills colic collapse constipation convulsion coughing cowardice crack up cyanosis damping deadening debilitate debilitation debility deplete devitalization diarrhea dilution dirty work disable dizziness do in do up donkeywork drag on drain droop drop dropsy drowsiness drudgery dulling dullness dysentery dyspepsia dyspnea edema effemination emaciation employment enervate enervation enfeeblement ennui etiolation evisceration exhaust exhaustion extenuation fag fag out faint fainting faintness feebleness fever fibrillation flabbiness flaccidity flag flux frazzle gasp get tired give out glut go on forever grind grow weary growth handiwork handwork harass heaviness hebetude hemorrhage high blood pressure hydrops hypertension hypotension icterus impotence inanimation inanition indifference indigestion industry inflammation insomnia irk itching jade jadedness jaundice knock out knock up labor labored breathing lackadaisicalness languidness languishment languor languorousness lassitude lenitude lentor lethargy lick lick of work lifelessness listlessness low blood pressure lumbago manual labor marasmus mitigation moil nasal discharge nausea necrosis oscitancy overfatigue overstrain overtire overweary pain pall pant paralysis passivity peter out phlegm play out poop poop out prostrate prostration pruritus puff puff and blow rash rat race reduction relaxation rheum run down run out satedness satiate sclerosis scut work seizure shock sink skin eruption slackening slavery sleepiness sloth slothfulness slowness sluggishness sneezing softening softness somnolence sore spadework spasm strengthlessness stroke stroke of work stupefaction stupor succumb supineness sweat tabes tachycardia task thinning tire tire out tire to death tiredness tiresome work toil torpidity torpidness torpitude torpor travail treadmill tucker tumor upset stomach use up vertigo vex vomiting wasting weaken weakening weakliness weakness wear wear down wear on wear out weariness weary wheeze wilt wind work world-weariness