1. (v.) To depreciate; to render as evil; to revile\.

2. (n. t.) To make bad or worse; to vitiate; to corrupt.

abuse adulterate afflict aggrieve alloy bastardize befoul bewitch blight brutalize canker cheapen coarsen condemn confound contaminate corrupt crucify curse damage debase debauch defile deflower degenerate degrade demoralize denature desecrate despoil destroy devalue disadvantage disserve distort distress do a mischief do evil do ill do wrong do wrong by doom envenom get into trouble harass harm hex hurt impair infect injure jinx maltreat menace mistreat misuse molest outrage persecute pervert play havoc with play hob with poison pollute prejudice prostitute ravage ravish savage scathe taint threaten torment torture twist ulcerate violate vitiate vulgarize warp wound wreak havoc on wrong