1. (v. t.) To make faulty or imperfect; to render defective; to contaminate\; to injure the substance or qualities of; to impair; to contaminate; to spoil; as, exaggeration vitiates a style of writing; sewer gas vitiates the air.

2. (v. t.) To cause to fail of effect, either wholly or in part; to make void; to destroy, as the validity or binding force of an instrument or transaction; to annul; as, any undue influence exerted on a jury vitiates their verdict; fraud vitiates a contract.

abate abolish abrogate adulterate alloy annihilate annul bastardize blemish bring to nothing brutalize buffer cancel cancel out canker cheapen coarsen come to nothing confound contaminate corrupt corrupted counterbalance damage debase debauch debauched defile deflower degenerate degrade delete demoralize denature deprave depraved depreciate depress desecrate despoil destroy devalue diminish distort downgrade frustrate harm hurt impair infect invalidate lower mar misuse negate negativate negative neutralize nullify offset pervert perverted poison pollute prejudice prostitute quash ravage ravish reduce revoke ruin soil spoil stultify sully suppress taint tarnish thwart twist ulcerate undermine undo violate vitiated void vulgarize warp weaken withdraw