1. (v. t.) To make foul, impure, or unclean; to defile; to contaminate\; to soil; to desecrate; -- used of physical or moral defilement.

2. (v. t.) To violate sexually; to debauch; to dishonor.

3. (v. t.) To render ceremonially unclean; to disqualify or unfit for sacred use or service, or for social intercourse.

4. (a.) Polluted.

abuse adulterate afflict aggrieve alloy bastardize befoul benasty bewitch blight booze up boozify canker cheapen coarsen condemn confound contaminate convert corrupt crock crucify curse cut damage debase debauch defalcate defile deflower degenerate degrade denaturalize denature deprave desecrate despoil destroy devalue dilute dirty disadvantage disserve distort distress divert do a mischief do evil do ill do wrong do wrong by doctor doctor up doom embezzle envenom fortify foul fuddle get into trouble harass harm hex hurt impair infect injure jinx lace maladminister maltreat menace mess mess up misapply misappropriate misemploy mishandle mismanage mistreat misuse molest nasty outrage overtake peculate persecute pervert pickle pilfer plaster play havoc with play hob with poison prejudice profane prostitute ravage ravish savage scathe soil souse spike spoil stain stew stone sully swack taint tamper with tarnish threaten tipsify torment torture twist ulcerate violate vitiate vulgarize warp water water down wound wreak havoc on wrong