(n.) The act of ruining, or the state of being ruined.

bane bankruptcy bloodbath blue ruin breakage breakdown breakup carnage collapse confusion consumption crack-up crippling damage damnation decimation depredation desolation despoilment despoliation destroyer destruction detriment devastation dilapidation disablement disintegration disorganization disrepair disruption dissolution encroachment harm havoc hecatomb hobbling holocaust hurt hurting impairment incapacitation infringement injury inroad loss maiming mayhem mischief mutilation perdition ravage ruin ruinousness sabotage scathe shambles sickening slaughter spoiling spoliation undoing vandalism waste weakening wrack wrack and ruin wreck