1. (v. t.) To spasm; to contract violently and irregularly, as the muscles of an animal convulse\; to shake with irregular spasms, as in excessive laughter, or in agony from grief or pain.

2. (v. t.) To agitate greatly; to shake violently.

afflict agitate agonize ail amuse beat beat up beguile bite bloody bug burn chafe churn churn up claw concuss crucify cut delight disarrange discompose disquiet distract distress disturb divert embroil enliven entertain excite excruciate exhilarate ferment fester flurry fracture one fret gall give pain gnaw grate grind gripe harrow hurt impale inflame inflict pain irritate kill kill by inches knock dead lacerate lancinate loosen up macerate martyr martyrize nip paddle pain perturb perturbate pierce pinch prick prolong the agony psych punish put to torture rack raise a laugh raise a smile rankle rasp recreate refresh regale relax rile rip ripple rock roil roughen rub ruffle rumple savage scarify shake shake up slay solace spook stab sting stir stir up swirl throw throw into confusion tickle titillate torment torture trouble tweak twist unsettle upset whip whip up whisk work up wound wow wring