Schmerz Slough of Despond blank despondency death wish dejectedness dejection depression despair despondency despondentness discouragement disheartenment dispiritedness down trip downcastness downer downheartedness drooping spirits heartlessness hopelessness lowness lowness of spirit malaise oppression pessimism self-destructive urge sinking heart spiritlessness suicidal despair taedium vitae weariness of life