(v. t.) To make like a brute; to make senseless, stupid, or unfeeling; to brutalize.

adulterate alloy boss brutify canker carnalize cheapen confound contaminate corrupt debase debauch defile deflower degenerate degrade denature deprave desecrate despoil devalue distort gnarl grain granulate horripilate infect knob misuse pervert pimple poison pollute popularize prostitute ravage ravish rough rough up roughen smooth stud taint tooth twist ulcerate violate vitiate vulgarize warp