LETTER OF TRANSMITTAL .

CONTENTS.

INTRODUCTION.

HISTORICAL REVIEW OF THE LITERATURE ON THE TOXICITY OF CAFFEIN.

ACUTE CAFFEIN INTOXICATION.

CHRONIC CAFFEIN INTOXICATION.

DISCUSSION OF RESULTS.

GENERAL SUMMARY AND CONCLUSIONS.

CAFFEIN BIBLIOGRAPHY.

Issued April 4, 1912.

U.S. DEPARTMENT OF AGRICULTURE,
BUREAU OF CHEMISTRY—BULLETIN No. 148.
H. W. WILEY, Chief of Bureau.

THE TOXICITY OF CAFFEIN:
AN EXPERIMENTAL STUDY
ON DIFFERENT SPECIES OF ANIMALS.

BY

WILLIAM SALANT,
Chief Pharmacological Laboratory, Division of Drugs,
AND
J. B. RIEGER,
Assistant Chemist.

WASHINGTON:
GOVERNMENT PRINTING OFFICE.
1912.