CAFFEIN BIBLIOGRAPHY.

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1. Abderhalden and Brahm. Zts. Physiol. Chem., 1909, 62: 133.2. Albers. Deut. Klin., 1852, 5: 577.

3. Amat. Diss. Paris, 1889.

4. Amory. Boston Med. Surg. J., 1868, 1: 261.

5. von Anrep. Arch. Ges. Phys., 1880, 21: 185.

6. Aubert. PflÜger's Arch., 1872, 5: 589.

7. Auer and Meltzer. J. Pharm. Exper. Ther., 1911, 2: 402.

8. Baldi. Terapia Moderna, 1891, 5: 617.

9. Bennett. Brit. Med. J., 1874, 2: 674.

10. Bernard, Claude. LeÇons sur les substances toxiques, Paris, 1857, p. 292.

11. Binz. Arch. Exper. Path. Pharm., 1878, 9: 31.

12. —— Ibid., 1891, 28: 197.

13. Brill. Diss. Marburg, 1861.

14. Buchheim and Eisenmenger. Beitr. Anat. Physiol., 1870, 5: 115.

15. Bunge and Schmiedeberg. Arch. Exper. Path. Pharm., 1876, 6: 233.

16. Chittenden. The Nutrition of Man, 1907.

17. Cogswell. Lancet (London), 1852, 2: 488.

18. Danilewski. Arch. Exper. Path. Pharm., 1894, 35: 105.

19. Drzewina. Compt. rend. Soc. biol., 1911, 70: 772.

20. Dumas and Pelletier. Ann. chim. phys., 1823, 24: 182.

21. Edmunds. J. Amer. Med. Assoc., 1907, 48: 1744.

22. Filehne. Arch. Phys., 1886, p. 72.

23. Fleischer and Loeb. Archives of Internal Medicine, 1909, 3: 78.

24. Focke. Arch. Pharm., 1903, 241: 678.

25. Frerichs. HandwÖrterbuch Phys., 1846, 3: 721.

26. FrÖhner. Monats. prakt. Tierh., 1892, 3: 529.

27. Gentilhomme. Bull. Soc. Med. Reims, 1867, 5: 93.

28. Gourewitch. Arch. Exper. Path. Pharm., 1907, 57: 314.

29. Guinard. Compt. rend. Soc. biol., 1900, 2 (2d ser.): 727.

30. ——. Compt. rend., 1893, 113: 520.

31. ——. La Morphine et l'apomorphine, Paris, 1903.

32. Gunn. Arch. Int. Pharm. Ther., 1909, 19: 319.

33. Hale. U. S. Public Health and Marine-Hospital Service. Hyg. Lab. Bul. 53, p. 43.

34. Harrington. Amer. J. Phys., 1898, 1: 385.

35. Hatcher. J. Amer. Med. Assoc., 1910, 60: 746.

36. Henneguy. Diss. Montpellier, 1875.

37. Hofmeister. Arch. Exper. Path. Pharm., 1894, 33: 198.

38. Hoppe. Écho MÉd. NeuchÂtel, 1858.

39. Hunt. U. S. Public Health and Marine-Hospital Service. Hyg. Lab. Bul. 69, p. 51.

40. ——. Ibid., Bul. 33.

41. Igersheimer and Stami. Arch. Exper. Path. Pharm., 1909, 61: 18.

42. Jacobi and Golowinski. Arch. Exper. Path. Pharm., Supplement Bd. 1908, p. 286.

43. Jobst. Ann. Pharm., 1838, 25: 63.

44. Johansen. Diss. Dorpat, 1869.

45. Kobert. Lehrbuch der Intoxicationen, 1902, 1: 24.

46. KÖster. Arch. Gesamt. Phys., 1910, 136: 17.

47. KrÜger and Schmidt. Ber. d. chem. Ges., 1899, 32: 2677.

48. Kurzak. Zts. Aerzte zu Wien, 1860, n. f., 3: 625.

49. Lapicque. Compt. rend. Soc. biol., 1910, 68: 1007.

50. Leblond. Diss. Paris, 1883.

51. Lehmann, C. G. Lehrbuch fÜr physiolische Chemie, 1842, 1: 336.

52. Lehmann, J. Ann. chim. pharm., 1853, 87: 205.

53. Leven. Arch. Phys., 1868, 1: 180.

54. Livon. Compt. rend. Soc. biol., 1897, 4: 979.

55. Maurel. Compt. rend. Soc. biol., 1907, 62: 897.

56. ——. Ibid., 1909, 66: 782.

57. ——. Ibid., 1910, 69: 5.

58. Meltzer and Auer. J. Exper. Med., 1905, 7: 59.

59. Mitchell. J. Phys., 1862, 5: 109.

60. Mitscherlich. Diss. Berlin, 1859.

61. Moschkowitsch. Arch. Pharm., 1903, 241: 358.

62. Mulder. J. prakt. Chem., 1838, 15: 280.

63. ——. Poggendorff's Ann. Physik Chem., 1838, 43: 180.

64. Neubauer. Arch. Exper. Path. Pharm., 1901, 46: 133.

65. Noe. Arch. Int. Pharm. Ther., 1904, 12: 160.

66. OphÜls. Proc. Soc. exper. biol. med., 1911, 8: 75.

67. Oudry. Nouvelle Bibliothek MÉdicale, 1827; Geiger's Magazin Pharm., 1827, 19: 49.

68. Parisot. Diss. Paris, 1890.

69. Pelletier. J. Pharm., 1826, 12: 229; also quoted by Brill, 3.

70. Peretti. Diss. Bonn, 1875.

71. Pfaff. Schweigger-Seidel, 1831, 1: 87.

72. Pfaff and Liebig. Ann. Pharm., 1832, 1: 17.

73. Pohl. Arch. Exper. Path. Pharm., Suppl. Bd., 1908, p. 427.

74. Pratt. Boston Med. Surg. J., 1868, 2: 82.

75. Robiquet. Dict. Tech., Paris, 1823, 4: 59.

76. Rost. Diss. Heidelberg, 1895.

77. Runge. Neuste phyto-chem. Entdeckungen, Breslau, 1820.

78. Salant. U. S. Dept. Agr., Bureau of Chemistry Cir. 81.

79. Schmiedeberg and Bunge. Arch. Exper. Path. Pharm., 1874, 2: 62.

80. ——. Ibid., 1910, 62: 296.

81. Sollman and Brown. J. Amer. Med. Assoc., 1905, 45: 229.

82. Strecker. Ann. Chem. Pharm., 1861, 118: 151.

83. Stuhlmann and Falck. Arch. path. Anat. Phys., 1857, 11: 324.

84. Thierfelder and von Mering. Zts. physiol. Chem., 1885, 9: 511.

85. Voit. Untersuch. Über den Einfluss des Kochsalzes, des Kaffes... MÜnchen, 1860.

86. Zalesky. Hoppe-Seyler Med. Chem. Untersuch., Berlin, 1866, 85-116.

[A] The small figures refer to the bibliography at the end of this bulletin.

[B] Survived first dose.

[C] Time of injection inadvertently omitted, but was probably not slower than in the other cases of this series.

[D] Cat probably old; had been in the laboratory for several weeks before the experiment. Gained in weight 175 grams.

[E] A case of accidental poisoning reported recently by Wichura (MÜnich. Med. Woch., 1911, No. 30, p. 1618) throws some doubt on the accepted view that the susceptibility of young children to morphin is greater than that of adults. Wichura also found that the therapeutic doses of codein preparations ordinarily recommended for children in pleuritic cough are not effective in this condition.

Transcriber's Notes

Obvious typographical errors have been corrected, but variations in spelling, punctuation and hyphenation have been retained.

Rabbit 396. The date August 15 has been corrected to August 19.

The data for Rabbit 123 is presented as printed in the original, although it is likely that the Caffein per kilo. values should be preceded by a decimal point (or that the heading should be Mg.).

Standard footnotes are identied alphabetically. Numeric references within the text refer to the bibliography.

The headings of Table 18 have been abbreviated for clarity on small screens.





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