against the grain against the tide against the wind antagonistic antipathetic at cross-purposes at daggers at daggers drawn at feud at issue at loggerheads at odds at square at strife at variance at war with athwart clashing contra contradictory contrariwise contrary counter cranky cross differing disaccordant disagreeable disagreeing discordant discrepant disharmonious disproportionate dissident dissonant divergent eyeball-to-eyeball grating hostile immiscible in confrontation in hostile array in opposition inaccordant incompatible inharmonious jangling jarring negative out of accord out of whack repugnant uncongenial unharmonious up in arms variant with crossed bayonets