baleful baneful barren bootless choking constrictive contrary corroding corrosive corrupting corruptive crosswise damaging deadly deleterious detrimental disadvantageous disserviceable distressing effete empty etiolated fatuitous fatuous feckless fruitless futile harmful hindering hindersome hurtful in the way inadequate inane ineffective ineffectual inefficacious inhibiting inhibitive injurious inoperative interrupting interruptive invalid lethal malefic malevolent malign malignant mischievous noisome noxious nugacious nugatory obstructing obstructive obstruent occlusive of no force ominous pernicious poisonous prejudicial repressive restrictive scatheful sterile stifling strangling suppressive toxic troublesome unavailing useless vain venenate veneniferous venenous venomous vicious virulent