ablate abrade abrase abrasion acerbity acid acidity acidulousness acridity acridness acrimony afflict affliction aggravate aggravation agonize ail anger animosity annoy annoyance arouse arrogance asperity astringence astringency audacity autacoid bad humor bad temper badger balls bark bedevil bile bilge biliousness bite bitter cup bitter draft bitter draught bitter pill bitter resentment bitterness bitterness of spirit blain bleb blemish blister blob bloody boss bother bow brashness brass brazen boldness brazenness break bubble bulb bulge bulla bump bunch burden burden of care burl burn burn up button cahot cankerworm of care care causticity causticness chafe chalone check cheek chide chine chip choler chutzpah claw clump conceit concussion condyle confidence convex convulse corrosiveness crack crackle craze cross crown of thorns crucify crust curse cut digestive secretion discontent distress disturb dowel ear effrontery embitterment encumbrance endocrine enrage erase erode exacerbate exacerbation exasperate exasperation excoriate excruciate exercise face fester file flange flap flash burn fracture fray frazzle fret front gall and wormwood gash gastric juice get give pain gnarl gnashing of teeth gnaw gnaw away goad grate grate on gravel graze grievance grind gripe grit guts handle harass hard feelings harrow harry harshness haughtiness heartburning hector heroics hill hormone hubris hump hunch hurt ill humor ill nature ill temper impertinence improvidence imprudence impudence incense incise incision indiscretion inflame inflict pain infliction infuriate injudiciousness injure injury insolence intestinal juice irk irritant irritate irritation jog joggle kill by inches knob knot knur knurl lacerate laceration lesion lip load loftiness loop lordliness lump maim make mincemeat of martyr martyrize maul mole mordacity mortal wound mountain moxie mucus mutilate mutilation nag needle nerve nettle nevus nip nub nubbin nubble nuisance oppression overbearance overboldness overcarelessness overconfidence oversureness overweeningness pack of troubles pain pancreatic juice papilloma peck of troubles peg pester pierce pinch plague poison pomposity presumption prick pride