1. (a.) Not easy; difficult.

2. (a.) Restless; disturbed by pain, anxiety, or the like; disquieted; perturbed.

3. (a.) Not easy in manner; constrained; stiff; awkward; not graceful; as, an uneasy deportment.

4. (a.) Occasioning want of ease; constraining; cramping; disagreeable; unpleasing.

abashed afflicted agitated all nerves all-overish ambiguous anguished antsy antsy-pantsy anxious anxioused up apprehensive beefing bellyaching beset bitching borderline bored bothered breathless careful cast down chafing chagrined chapfallen cheerless complaining complaintful concerned confused crabbing crabby cranky croaking depressed disappointed discomfited discomforted discomposed disconcerted discontented disgruntled disgusted displeased disquieted dissatisfied distressed disturbed doubtable eager edgy embarrassed envious excitable excited faultfinding fearful feverish fidgety flurried flustered fluttery foreboding fretful fretting frightened fussy grim griping grouchy grousing growling grumbling hasty high-strung hopped-up hung up ill at ease impatient impetuous in a lather in a pucker in a stew in a sweat irritable jittery joyless jumpy malcontent malcontented misgiving mortified murmuring muttering nauseated nauseous nerves on edge nervous nervy on edge on tenterhooks out of countenance out of humor overanxious overapprehensive overstrung panicky peevish perturbed petulant pleasureless precarious prey to malaise put-out put-upon querulant querulous rebellious repelled resentful restive restless revolted ruffled sad shaken shaken up shaky sickened solicitous squirming squirmy stirred up strained suffering angst sulky suspect suspenseful tense troubled troublous turbulent unaccepting unaccommodating uncertain uncomfortable unfulfilled ungratified unhappy unpatient unpeaceful unquiet unrestful unsatisfied unsettled unsure upset uptight whiny worried zealous