Dictionary
1. (n.) A solution of continuity in any of the soft parts of the body, discharging purulent matter, found on a surface, especially one of the natural surfaces of the body, and originating generally in a constitutional disorder; a sore discharging pus. It is distinguished from an abscess, which has its beginning, at least, in the depth of the tissues.

2. (n.) Fig.: Anything that festers and corrupts like an open sore; a vice in character.

3. (v. t.) To ulcerate.

Thesaurus
abdominal hernia abscess aposteme bane bed sore blain bleb blight blister boil bubo bulla bunion cancer canker canker sore carbuncle chancre chancroid chilblain cold sore colitis curse disease diverticulitis diverticulosis duodenal ulcer duodenitis eruption eschar esophagal ulcer esophagitis felon fester festering fever blister fistula furuncle furunculus gastritis gathering gumboil hemorrhoids hiatal hernia inflammation kibe lesion megacolon papula papule paronychia parulis peptic ulcer peritonitis pestilence petechia piles pimple plague pock poison polyp pustule rising scab scourge soft chancre sore stigma stomach ulcer sty suppuration swelling tubercle ulceration wale welt wheal whelk whitlow wound
                                                                                                                                                                                                                                       

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