1. (a.) Having no sleep; wakeful.

2. (a.) Having no rest; perpetually agitated.

Argus-eyed agile alert alive all ears all eyes ardent assiduous attentive aux aguets awake bright constant continuing custodial diligent disturbed dogged eagle-eyed enduring energetic faithful fervent guarded hard hardworking hawk-eyed immutable inalterable indefatigable indomitable industrious insistent insomniac insomnious invincible keen keen-eyed laborious lasting lidless loyal never idle never-tiring nimble observant obstinate on guard on the on the alert on the ball on the job on the lookout on the watch open-eyed patient patient as Job permanent perseverant persevering persistent persisting pertinacious plodding plugging preoccupied prompt prudent qui vive quick rapt ready relentless resolute restless sedulous sharp sharp-eyed single-minded slogging slumberless smart stable steadfast steady strenuous stubborn tenacious tireless unabating unblinking unconquerable undaunted undiscouraged undrooping unfailing unfaltering unflagging unflinching unintermitting uninterrupted unnodding unrelaxing unrelenting unremitting unsleeping unsparing unswerving untiring unwavering unwearied unwearying unwinking utterly attentive vehement vigilant wakeful wary watchful weariless wide-awake with open eyes zealous