1. (n.) A sign, stamp, or mark impressed, as by a seal.

2. (v. t.) Especially, the name of any person, written with his own hand, employed to signify that the writing which precedes accords with his wishes or intentions; a sign manual; an autograph.

3. (n.) An outward mark by which internal characteristics were supposed to be indicated.

4. (n.) A resemblance between the external characters of a disease and those of some physical agent, for instance, that existing between the red skin of scarlet fever and a red cloth; -- supposed to indicate this agent in the treatment of the disease.

5. (n.) The designation of the key (when not C major, or its relative, A minor) by means of one or more sharps or flats at the beginning of the staff, immediately after the clef, affecting all notes of the same letter throughout the piece or movement. Each minor key has the same signature as its relative major.

6. (n.) A letter or figure placed at the bottom of the first page of each sheet of a book or pamphlet, as a direction to the binder in arranging and folding the sheets.

7. (n.) The printed sheet so marked, or the form from which it is printed; as, to reprint one or more signatures.

8. (v. t.) That part of a prescription which contains the directions to the patient. It is usually prefaced by S or Sig. (an abbreviation for the Latin signa, imperative of signare to sign or mark).

9. (v. t.) To mark with, or as with, a signature or signatures.

ID card John Hancock OK Smyth sewing X accent accent mark acceptance accommodation acknowledgment acknowledgments adjustment affirmance affirmation approbation approval arrangement article authentication authorization autograph back back matter backing badge banner bar bastard title bibliography bibliopegy binder board binding book book cloth book cover book jacket bookbinding bookcase by-line calligram calling card cancel card case casemaking casing-in catch line catchword certification chapter character characteristic christcross cipher citation clause closing collating collating mark colophon conclusion confession confirmation contents contents page copyright page countermark countersign countersignature counterstamp cover credentials credit line cross custos dedication device differentia direct dog tag dot dust cover dust jacket earmark endleaf endorsement endpaper endsheet errata expression mark fascicle fermata flyleaf folding folio footband fore edge foreword front matter gathering gluing-off go-ahead green light half-title page hallmark hand hard binding head headband hold identification identification badge identification tag idiosyncrasy image imprimatur imprint index indicant indicator initials ink inscription insignia introduction jacket key signature keynote lead leaf letter of introduction library binding ligature lining lining-up makeup mark mark of signature measure mechanical binding metronomic mark monogram nod notarization notation note number okay page paragraph passage pause peculiarity perfect binding permission phrase picture plastic binding preface preliminaries presa press card property ratification recto reference representation representative reverso rounding rubber stamp running title saddle stitching sanction seal sealing section segno sentence serial number settlement sewing sheet side sewing sigil sign sign manual signal signet signing slipcase slipcover slur smashing soft binding solemnization spiral binding stamp stamp of approval stamping stapling subscribe subscription subtitle sure sign swell symbol symptom table of contents tail tailband telltale sign tempo mark tessera text the nod theme song tie time signature tipping title title page trademark trait tribute trim size trimming type page validation verse verso vinculum visa vise visiting card warrant wire stitching wrapper