1. (v. i.) To perform a work or labor; to exert power or strength, to act\.

2. (v. i.) To produce an appropriate physical effect; to issue in the result designed by nature; especially (Med.), to take appropriate effect on the human system.

3. (v. i.) To act or produce effect on the mind; to exert moral power or influence.

4. (v. i.) To perform some manual act upon a human body in a methodical manner, and usually with instruments, with a view to restore soundness or health, as in amputation, lithotomy, etc.

5. (v. i.) To deal in stocks or any commodity with a view to speculative profits.

6. (v. t.) To produce, as an effect; to cause.

7. (v. t.) To put into, or to continue in, operation or activity; to work; as, to operate a machine.

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