1. (v. t.) To destroy the organic texture and vital functions of; to produce gangrene in.

2. (v. t.) To destroy the active powers or essential qualities of; to change by chemical action.

3. (v. t.) To deaden by religious or other discipline, as the carnal affections, bodily appetites, or worldly desires; to bring into subjection; to abase; to humble.

4. (v. t.) To affect with vexation, chagrin, or humiliation; to humble; to depress.

5. (v. i.) To lose vitality and organic structure, as flesh of a living body; to gangrene.

6. (v. i.) To practice penance from religious motives; to deaden desires by religious discipline.

7. (v. i.) To be subdued; to decay, as appetites, desires, etc.

abash break up bring down canker cast down castigate chagrin chasten confound confuse control corrupt crumble crumble into dust crush decay decompose deflate degrade discipline discomfit discompose disconcert disgrace disintegrate disturb downgrade embarrass fall into decay fall to pieces fester gangrene go bad go to pieces humble humiliate let down mildew mold molder necrose punish put down put out put to shame putrefy putresce rankle rebuff reduce rot shame sphacelate spoil subdue subjugate suppress suppurate throw into confusion upset