1. (n.) The state or quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart.

2. (n.) Unfavorableness; evil nature.

3. (n.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.

4. (n.) The state of being a malignant.

balefulness banefulness bitchiness communicability contagiousness cussedness deadliness despite destructiveness detrimentalness devilment devilry deviltry evil intent fatality grudge harmfulness hatefulness hurtfulness ill will infectiousness infectivity iniquitousness injuriousness invidiousness lethality maleficence malevolence malice malice aforethought malice prepense maliciousness malignance malignity meanness mischievousness mortality nastiness noisomeness noxiousness ominousness orneriness perniciousness poison poisonousness spite spitefulness spleen toxicity unhealthiness venom venomousness viciousness virulence virulency wickedness