(n.) The act of inflicting agonizing pain, or the state of being thus afflicted; that which excruciates; torture.

aching heart affliction agonizingness agony of mind anguish atrocious pain bale bitterness bleeding heart broken heart care carking care crucifixion crushing death agonies death groan death rattle death struggle death throes deathbed deathwatch depression depth of misery desolateness desolation despair distress dolor dying breath excruciatingness excruciation extremity final extremity grief heartache heartbreak heartfelt grief heartgrief heartsickness heavy heart infelicity lamentation languishment last agony last breath last gasp martyrdom martyrization melancholia melancholy misery moribundity pain pangs passion pining prostration rack sadness sorrow sorrowing suffering suicidal despair throes throes of death torment tormentingness torture torturousness trouble woe wretchedness