1. (n.) The act of exasperating or the state of being exasperated; irritation; keen or bitter anger.

2. (n.) Increase of violence or malignity; aggravation; exacerbation.

aggravation agitation amplification animation annoyance annoyingness arousal arousing augmentation bad news bedevilment besetment bore bother botheration bothersomeness contentiousness crashing bore deepening deliberate aggravation deterioration devilment difficulty disapprobation disapproval discontent displeasure dissatisfaction dogging downer drag electrification embittering embitterment enhancement enlargement exacerbation excitation excitement exhilaration firing fomentation galvanization harassment harrying headache heightening hounding incitation incitement increase inflammation infuriation instigation intensification irksomeness irritant irritation lathering up magnification molestation nuisance pep rally pep talk persecution perturbation peskiness pest pester pestiferousness plague plaguesomeness pother problem provocation provokingness rabble-rousing resentfulness resentment sharpening souring steaming up stimulation stimulus stirring stirring up stirring-up tiresomeness trial trouble troublesomeness vexation vexatiousness wearisomeness whipping up working up worriment worrisomeness worry worsening