1. (v. t.) To withdraw; to alienate; as an estranged wife or husband\; hence, reflexively, to keep at a distance; to cease to be familiar and friendly with.

2. (v. t.) To divert from its original use or purpose, or from its former possessor; to alienate.

3. (v. t.) To alienate the affections or confidence of; to turn from attachment to enmity or indifference.

abrupt aggravate alien alienate antagonize break up cast off cast out come between cut adrift cut off cut out delete depart disaffect disarticulate disconnect disengage disjoin disjoint dissociate disunify disunite divide divorce eject embitter envenom exacerbate expel fan the flame heat up infuriate irritate isolate leave light the fuse madden make trouble part pit against provoke pull away pull back pull out segregate separate sequester set against set apart set aside set at odds set at variance set on sever shut off sic on sow dissension split stand aloof stand apart stand aside step aside stir up trouble subtract sunder throw off throw out uncouple unyoke wean withdraw