1. (v. t.) To distinguish or mark by a specific difference\; to effect a difference in, as regards classification; to develop differential characteristics in; to specialize; to desynonymize.

2. (v. t.) To express the specific difference of; to describe the properties of (a thing) whereby it is differenced from another of the same class; to discriminate.

3. (v. t.) To obtain the differential, or differential coefficient, of; as, to differentiate an algebraic expression, or an equation.

4. (v. i.) To acquire a distinct and separate character.

adapt adjust alter analyze anatomize argue atomize be characteristic be indicative of be significant of be symptomatic of bespeak betoken break up calibrate calibrated change characterize chop logic comprehend connote contradistinguish contrast convert decrease define demarcate demark denominate denote describe desynonymize differ difference discern disclose discriminate disequalize disjoin display dissent distinguish disunify divaricate diverge diversify divide draw the line earmark entail express extricate give evidence give token gradational grade gradual graduate graduated hierarchic highlight hint identify increase indicate individualize individuate involve keynote make a distinction manifest mark mark off mark out mark the interface mean modify note oppose particularize personalize pick out progressive refine a distinction regular relieve reveal scalar screen screen out segregate select separate set a limit set apart set off set the pace set the tone sever severalize shade off show sieve sieve out sift sift out signify sort sort out sound the keynote specialize split hairs stand for subdivide subtilize suggest symptomatize symptomize tell apart testify transform transmute understand variate variegate vary winnow