1. (a.) Causing destruction; tending to bring about ruin, death, or devastation; ruinous; fatal; productive of serious evil; mischievous; pernicious; -- often with of or to; as, intemperance is destructive of health; evil examples are destructive to the morals of youth.

2. (n.) One who destroys; a radical reformer; a destructionist.

adverse annihilative antithetical bad baleful baneful black brutal calamitous cataclysmal cataclysmic catastrophic catching communicable condemnatory conflicting consuming consumptive contagious contradictory contrary critical damaging dangerous deadly death-bringing deathful deathly deleterious demolishing demolitionary depredatory derogatory desolating destroying detrimental devastating dire disapproving disastrous disparaging doomful envenomed fatal fateful fell feral fratricidal grievous harmful hurtful infectious infective injurious internecine killing lethal malign malignant mephitic miasmal miasmatic miasmic mortal negative nihilist nihilistic noxious opposed opposing pernicious pestiferous pestilential poisonous ravaging ruining ruinous savage self-destructive shattering subversionary subversive suicidal toxic toxicant toxiferous tragic unfavorable unwholesome vandalic vandalish vandalistic venenate veneniferous venenous venomous virulent wasteful wasting withering wreckful