1. (prep.) In spite of; notwithstanding; against, or in defiance of; as, despite his prejudices\.

2. (n.) Malice; malignity; spite; malicious anger; contemptuous hate.

3. (n.) An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.

4. (n.) To vex; to annoy; to offend contemptuously.

Schadenfreude abhorrence abomination affront airs arrogance aspersion at all costs at any cost atrocity audacity aversion bold front boldness brash bearing brashness brassiness bravado brazenness brickbat bumptiousness cattiness cheekiness clannishness cliquishness cockiness cold shoulder contempt contemptuousness contumacy contumely cut daring daringness defial defiance defying derision despisal detestation discourtesy disdain disdainfulness disfavor disgust dislike disparagement disregard distaste dump enormity even with flouting gibe gloating pleasure grudge harm hate hatred hauteur humiliation hurt ignoring ill will impertinence impudence in defiance of in despite of in spite of incivility indignity injury insolence insult irregardless irrespective of jeer jeering loathing malevolence maliciousness malignancy malignity mock mockery notwithstanding offense outrage pertness put-down rebuff recalcitrance regardless regardless of regardless of cost rejection repudiation ridicule sauciness scoff scorn scornfulness scurrility slap slight sniffiness snobbishness snootiness snottiness snub sovereign contempt spite spite of spitefulness spleen spurning stubbornness superciliousness taunt toploftiness uncomplimentary remark unholy joy with