1. (n.) Want or absence of something necessary for completeness or perfection; deficiency; -- opposed to superfluity.

2. (n.) Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment.

3. (v. i.) To fail; to become deficient.

4. (v. t.) To injure; to damage.

abandon abnormality acute disease affection affliction ailment allergic disease allergy apostacize apostatize arrearage atrophy back out bacterial disease betray birth defect birthmark blackhead bleb blemish blight blister bolt break break away bug bulla cardiovascular disease catch change sides check chronic disease cicatrix circulatory disease comedo complaint complication condition congenital defect crack crater craze dearth defacement defalcation default defection deficiency deficiency disease deficit deformation deformity degenerate degenerative disease depart desert disability discontinuity disease disfiguration disfigurement disorder distemper distortion drawback endemic endemic disease endocrine disease epidemic disease error escape failing failure fall away fall off fault faute flaw foible forsake frailty freckle functional disease fungus disease gap gastrointestinal disease genetic disease go go back on go over handicap hemangioma hereditary disease hiatus hickey hole iatrogenic disease illness imperfection inadequacy indisposition infectious disease infirmity insufficiency interval irregularity keloid kink lack lacuna leave lentigo let down liability little problem malady malaise mark milium miss missing link mistake mole morbidity morbus muscular disease need needle scar neurological disease nevus nutritional disease occupational disease omission organic disease outage pandemic disease pathological condition pathology pimple pit plant disease pock pockmark port-wine mark port-wine stain privation problem protozoan disease psychosomatic disease pull out pustule quit rat reject renegade renege renounce repudiate respiratory disease rift rockiness run out on scab scantiness scar scarceness scarcity scratch sebaceous cyst secede secondary disease seediness sell out shortage shortcoming shortfall sickishness sickness signs snag something missing split spurn stain strawberry mark sty switch switch over symptomatology symptomology symptoms syndrome taint tergiversate the pip track turn turn against turn cloak turn traitor twist ullage urogenital disease verruca vesicle vice virus disease vulnerable place wale want wantage warp wart wasting disease weak link weak point weakness weal welt wen whitehead withdraw worm disease