(n.) A condition of endemic or inherited idiocy, accompanied by physical degeneracy and deformity (usually with goiter), frequent in certain mountain valleys, esp. of the Alps.

acromegaly amentia arrested development backwardness blithering idiocy choriocarcinoma diabetes diabetes insipidus diabetes mellitus dwarfism giantism half-wittedness hyperglycemia hyperparathyroidism hypo-ovarianism hypothyroidism idiocy idiotism imbecility infantilism insanity mental defectiveness mental deficiency mental handicap mental retardation mongolianism mongolism mongoloid idiocy moronism moronity panhypopituitarism pheochromocytoma profound idiocy retardation retardment sexual precocity simple-wittedness simplemindedness simpleness simplicity subnormality thyrotoxicosis toxic goiter