1. (n.) The quality or state of being bitter, sharp, or acrid, in either a literal or figurative sense; implacableness; resentfulness; severity; keenness of reproach or sarcasm; deep distress, grief, or vexation of mind.

2. (n.) A state of extreme impiety or enmity to God.

3. (n.) Dangerous error, or schism, tending to draw persons to apostasy.

absolute zero acerbity aching heart acid acidity acidness acidulousness acridity acridness acrimony agony agony of mind algidity anguish animosity animus antagonism apologies asperity astringence astringency attrition ayenbite of inwit bad blood bale bile bite bitingness bitter feeling bitter pill bitter resentment bitterness bitterness of spirit bleakness bleeding heart briskness broken heart causticity causticness cheerlessness chill chilliness choler cold coldness comfortlessness contriteness contrition cool coolness coolth corrosiveness crispness crushing cryogenics cryology cuttingness decrease in temperature depression depth of misery desolation despair discomfort dismalness distress distressfulness dreariness edge enmity extremity feud fierceness freezing point freshness frigidity frostiness gall gall and wormwood gelidity gnashing of teeth grief grievousness grip hard feelings harshness hatred heartache heartburning heavy heart hostility iciness ill blood ill feeling ill will incisiveness inclemency infelicity intense cold joylessness keenness lamentability lamentation low temperature melancholia melancholy misery mordacity mordancy mournfulness nip nippiness pain painfulness pathos piercingness piquancy pitiability pitiableness pitifulness poignancy point prostration pungency rancor rankling rawness regret regretfulness regrets regrettableness regretting remorse remorse of conscience remorsefulness repining resentment rigor roughness sadness severity shame shamefacedness shamefastness shamefulness sharp air sharpness slow burn soreness sorriness sorrow sorrowfulness sourness spleen stabbingness sting stridency stringency suicidal despair tartness teeth trenchancy vehemence vendetta venom violence virulence vitriol wistfulness woe woebegoneness woefulness wretchedness