1. (n.) Violent contest or striving.

2. (n.) Pain so extreme as to cause writhing or contortions of the body, similar to those made in the athletic contests in Greece; and hence, extreme pain of mind or body; anguish; paroxysm of grief; specifically, the sufferings of Christ in the garden of Gethsemane.

3. (n.) Paroxysm of joy; keen emotion.

4. (n.) The last struggle of life; death struggle.

aching heart affliction agonizingness agony of mind anguish atrocious pain bale bitterness bleeding heart broken heart care carking care crucifixion crushing death agonies death groan death rattle death struggle death throes deathbed deathwatch depression depth of misery desolateness desolation despair distress dolor dying breath excruciatingness excruciation extremity final extremity grief heartache heartbreak heartfelt grief heartgrief heartsickness heavy heart infelicity lamentation languishment last agony last breath last gasp martyrdom martyrization melancholia melancholy misery moribundity pain pangs passion pining prostration rack sadness sorrow sorrowing suffering suicidal despair throes throes of death torment tormentingness torture torturousness trouble woe wretchedness