Among all the signal inventions, discoveries, and improvements of the age, social and material, scientific and mechanical, few, perhaps, are fraught with graver possibilities for good and evil than the great achievement of recent medicine—the development, if it should not more properly be called the discovery, of anÆsthetics. Steam has revolutionized mechanics; the locomotive, the steam-hammer, and the power-loom, the creation of the railway and the factory system, have essentially modified social as well as material civilization; and it is possible at least that electric lights and motors, telegraphs and telephones, may produce yet greater consequences. This last century has been signalized by greater mechanical achievements than the whole historic period since the discovery of iron. But in obvious, immediate influence on human happiness, it is quite conceivable that the discovery of chloroform, ether, and other anÆsthetics—the diffusion of chloral, opium, and other narcotics, putting them within the reach of every individual, at the command of men and women, almost of children, independently of medical advice or sanction—may be, for a time at least, more important than those inventions which have changed the fundamental conditions of industry, or those which may yet change them once more. It is difficult for the rising generation to realize that state of medicine, and especially of surgery, which old men can well remember; when every operation, from the extraction of a bad tooth to the removal of a limb, must be performed upon patients in full possession of their senses. In those days the horror with which men and women, uninfluenced by scientific enthusiasm, now regard the alleged tortures of vivisection was hardly possible. Thousands of human beings had yearly to undergo—every man, woman, and child might have to undergo—agonies quite as terrible as any that the most ardent advocate of the rights of animals, the most vivid imagination excited by fear for dearly loved dumb companions, ascribes to the vivisector’s knife. It may well be doubted whether the highest brutes are capable of suffering any pain comparable with that of hardy soldiers or seamen—much less with that of sensitive, nervous men, and delicate women—when the surgeon’s blade cut through living, often inflamed tissues, generally rendered infinitely more sensitive by previous disease or injury, while the brain was fully, intensely conscious; every nerve quivering with even exaggerated sensibility. The brutes, at any rate, are spared the long agony of anticipation, and at least half the tortures of memory. They may fear for a few minutes; our fathers and mothers lay in terror for hours and days, nay, persons of vivid imagination must have suffered acutely through half a lifetime, in the expectation that, soon or late, their only choice might lie between excruciating temporary torture and a death of lingering hopeless anguish. No gift of God, perhaps, has been so precious, no effort of human intellect has done more to lessen human suffering and fear, to take from life much of its darkest evil and horror, than anÆsthesia as developed during the last fifty years. True that in the case of severe operations it is as yet beyond the power of medicine to give complete relief. If spared the torture of the operation, the patient has yet to endure the cruel smart that the knife leaves behind. But the relief of previous terror, of the awful, unspeakable, and, to those who never felt it, almost inconceivable agony endured while the flesh was carved, and the bone sawn, have disappeared from the sick room and the hospital.

Narcotics should be carefully distinguished from anÆsthetics. Their use is different, not in degree only, but in character and purpose. Their legitimate object is two-fold: primarily, in a limited number of cases, to relieve or mitigate pain temporarily or permanently incurable; but secondarily and principally to cure what to a large and constantly increasing class in every civilized country is among the severest trials attendant on sickness, over-work, or nervous excitement—that loss of sleep which is a terrible affliction in itself, and aggravates, much more than inexperience would suppose, every form of suffering with which it is connected. Nature mercifully intended that prolonged intolerable pain should of itself bring the relief of sleep or swooning; and primitive races like the Red Indian, living in the open air, with dull imagination and insensible nerves, still find such relief. The victims of Mohawk and Huron tortures have been known, during a brief intermission of agony, to sleep at the stake till fire was used to awaken them. But among the many drawbacks of civilized life must be counted the tendency of artificial conditions to defeat some of Nature’s most merciful provisions. The nerves of civilized men are too sensitive, the brains developed by hereditary culture and constant exercise are too restless, to obtain from sleep that relief in pain, especially prolonged pain, that nature apparently intended. Many of us, even in sleep, are keenly sensitive to suffering, at least to chronic as distinguished from acute pain, to dull protracted pangs like those of rheumatism, ear-ache, or tooth-ache. A little sharper pain, and sleep becomes impossible. The sufferer is not only deprived of the respite that slumber should afford, but insomnia itself enhances his sensibility, besides adding a new and terrible torment of its own. Artificial prevention of sleep was notoriously among the most cruel and the most certainly mortal of mediÆval or barbaric tortures. The sensations of one who has not slept for several nights, beginning with a restless, unnatural, constantly increasing consciousness of the brain, its existence and its action, passing by degrees into an acute, unendurably distressing irritation of that organ—generally unconscious or insensible, probably because its habitual sensibility would be intolerable—are indescribable, unimaginable by those who have not felt them; and seem to be proportionate to the activity of the intellect, the susceptibility of nerve and vitality of temperament—the capacity for pain and pleasure. In a word, the finer the physical and nervous character, the more terrible the torment of sleeplessness. A little more and the patient is confronted with one of the most frightful forms of pain and terror, the consciousness of incipient insanity. But long before reaching this stage, sleeplessness exaggerates pain and weakens the power of endurance, quickens the sensibility of the nerves, enfeebles the will, exacerbates the temper, produces a physical and nervous irritability which to an observer unacquainted with the cause seems irrational, unaccountable, extravagant, even frantic, but which afflicts the patient incomparably more than those, however near and however sensitive, on whom it is vented. Drugs, then, which enable the physician in most cases to check insomnia at an early stage—to secure, for example, in a case of chronic pain, six or seven hours of complete repose out of the twenty-four, to arrest a mischief which leads by the shortest and most painful route directly to insanity—are simply invaluable.

It may seem a paradox, it is a truism, to say that in their value lies their peril. Because they have such power for good, because the suffering they relieve is in its lighter forms so common, because neuralgia and sleeplessness are ailments as familiar to the present generation as gout, rheumatism, catarrh to our grandfathers, therefore the medicines which immediately relieve sleeplessness and neuralgic pain are among the most dangerous possessions, the most subtle temptations, of civilized and especially of intellectual life. Every one of these drugs has, besides its immediate and beneficial effect, other and injurious tendencies. The relief which it gives is purchased at a certain price; and in every instance the relief is lessened or rendered uncertain, the mischievous influence is enhanced and aggravated by repetition; till, when the use has become habitual, it has become pure abuse, when the drug has become a necessity of life it has lost the greater part if not the whole of its value, and serves only to satisfy the need which itself alone has created. Contrary to popular tradition, we believe that of popular narcotics opium is on the whole, if the most seductive, the least injurious; chloral, which at first passed for being almost harmless, is probably the most noxious of all, having both chemical and vital effects which approach if they do not amount to blood-poisoning. It is said (we do not affirm with what truth) that the subsequent administration of half a teaspoonful of a common alkali operates as an antidote to some of these specific effects. The bromide of potash, another favorite, especially with women, is less, perhaps, a narcotic proper than a sedative. It is said not to produce sleep directly, like chloral or opium, by stupefaction, but at least in small doses simply to allay the nervous irritability which is often the sole cause of sleeplessness. But in larger quantities and in its ultimate effects it is scarcely less to be dreaded than chloral. It has been recommended as a potent, indeed a specific and the only specific, remedy for sea-sickness. But the state to which, as its advocate allows, the patient must be reduced, a state of complete nervous subjection to the power of the drug, seems worse than the disease, save in its most cruel and dangerous forms. Such points, however, may be left to the chemist, the physician, or the physiologist; our purpose is rather to indicate briefly the social aspects of the subject, the social causes, conditions, and consequences of that narcotism which is, if not yet a prevalent, certainly a rapidly-spreading habit.

The desire or craving for stimulants in the most general sense of the word—for drugs acting upon the nerves whether as excitant or sedative agents—is an almost if not absolutely universal human appetite; so general, so early developed, that we might almost call it an instinct. Alcohol, of course, is the most popular, under ordinary circumstances the most seductive, and by far the most widely diffused of all stimulant substances. From the Euphrates to the Straits of Dover, the vine has been from the earliest ages second only to corn in popular estimation; wine, next to bread, the most prized and most universal article of human food. The connection between Ceres and Bacchus is found in almost every language as in the social life of every nation, from the warlike Assyrian monarchy, the stable hierocratic despotism of Egypt, to the modern French Republic and German Empire. Corn itself has furnished stimulant second in popularity to wine alone; the spirit which delighted the fiercer, sterner races of Northern Europe—Swede, Norwegian, and Dane, St. Olaf, and Harold Hardrada, as their descendants of to-day; and the ale of our own Saxon and Scandinavian ancestry, which neither spirit, cider, nor Spanish wine has superseded among ourselves. The vine, again, seems to have been native to America; but the civilized or semi-civilized races of the southern and central part of the Western Continent had other more popular and more peculiar stimulants, also for the most part alcoholic. The palm, again, has furnished to African and Asiatic tribes a spirit not less potent or less noxious, not less popular and probably not less primitive, than whiskey or beer. But where alcohol has been unknown, among races to whose habits and temperament it was alien, or in climates where so powerful an excitant produced effects too palpably alarming to be tolerated by rulers or law-givers royal or priestly, other and milder stimulants or sedatives are found in equally universal use. Till the white man introduced among them his own destructive beverages, till the “fire-water” spread demoralization and disease, tobacco was the favorite indulgence of the Red Indian of North America, and very probably of that mighty race which preceded them and seems to have disappeared before they came upon the scene—the Mound-builders, whose gigantic works bear testimony to the existence of an agriculture scarcely less advanced or less prolific, a despotism probably not less absolute than that of Egypt. Coffee has for ages been almost equally dear to the Arabs; tea has been to China all that wine is and was to Europe, probably from a still earlier period, and has taken hold on the Northern, as coffee and tobacco upon the Southern, branches of the Tartar race. Opium, or drugs resembling opium in character, have been found as well suited to the temper, as delightful to the taste, of the quieter and more passive Oriental races as wine to the Aryan and Semitic nations. The Malays, the Vikings of the East Indies, found in bhang a drug the most exciting and maddening in its effects of any known to civilized or uncivilized man; a substitute for opium or haschisch bearing much the same relation to those sedatives as brandy or whiskey to the light wines of Southern Europe.

The craving, then, is not artificial but natural; is not, as teetotalers fancy, for alcohol alone or primarily, but for some form of nervous excitement or sedative specially suited to climate or race. Tea, coffee, and tobacco, opium, haschisch and bhang, mata and tembe, are probably as old as wine, older than beer, and take just as strong a hold upon the national taste. The desire testifies to a felt and almost universal want; and the attempt to put down a habit proved by universal and immemorial practice to answer to a need, real and absolute—or if artificial easily created and permanent, if not ineradicable, beyond any other artificial craving or habit—seems doomed to failure; the desire not being for this or that stimulant, for wine or alcohol, but for some agent that gives a special satisfaction to the nerves, some stimulant, sedative or astringent. The discouragement of one form of indulgence, especially if that discouragement be artificial or forcible, not moral and voluntary, can hardly have any other result than to drive the votaries of alcohol, for example, upon opium, or those of opium upon some form of alcohol. Tea, coffee, and tobacco have done infinitely more than teetotal and temperance preaching of every kind to diminish the European consumption of wine, beer, and spirits. Men and even women never have been and never will be content with water or milk, or even with the unfermented juices of fruits; to say nothing of the extreme difficulty of preserving unfermented juices in those warmer climates to which they are best adapted.

It seems, however, that the natural craving, especially among women, or men not subject to the fiercer excitements of war, hunting, and open air life in general, is not for the stronger but for the milder stimulants. Ale was the favorite beverage of England, light wine of Southern Europe, till the Saracen invasion, the crusades, and finally the extension of commerce, familiarised the Western Aryans with the non-intoxicant stimulants of the East, and the discovery of America introduced tobacco. But the use of tea and coffee is not less, we might say, is more distinctly artificial than that of beer or wine. The taste for tobacco, as its confinement in so many countries and to so great an extent to one sex proves, is the most artificial of all.

It is plain, both from the climates and the character of the races among whom the sedative drugs or slightly-stimulant beverages have first and most widely taken root, that the preference for sedatives or gentle excitants is not accidental, but to a large extent dependent upon the temperament and habits of races or nations. Alcohol suits the higher, more energetic, active, militant races; and the fiercer and more militant the temper or habits, the stronger the intoxicant employed. It is not improbable that the first and strongest incitement to the use of alcohol, as of bhang, was the desire for that which a very unfair and ungenerous national taunt describes as Dutch courage. No race, probably, except their nearest kinsmen of England, was ever less dependent on the artificial boldness produced by stimulants than the stubborn soldiers and seamen of Holland. The beer-loving Teutons have never been, like the wine-drinkers of France, Italy, and Spain, a military, or even, like the Scandinavians, a thoroughly martial race. They will fight: none, Scandinavians, Soudanese, and Turks perhaps excepted, fight better or more stubbornly. It may well be that the adventurous, enterprising spirit of Englishmen and Scotchmen, displayed at sea rather than on land, and in semi-pacific quite as much as in warlike enterprise, is derived in large measure from the strong Scandinavian element in our national blood. The tea-drinking Chinamen, the Oriental lovers of haschisch and opium, have mostly been industrious rather than energetic, agricultural or pastoral rather than predatory. The coffee-drinking Arabs were not, till the days of Mahomet, a specially warlike race. Bandits or guerillas they were perforce; like every people which inhabits a country whose mountains or deserts afford a safe refuge to robbers but promise no reward to peaceful industry. No race, no class living in the open air, save in the warmer climates, no people given to energetic muscular labor or devoted to war, would be prompt to abandon alcohol in any of its forms for its milder Oriental equivalents. Tea and coffee were introduced at a time when manufactures and in-door-life were gaining ground in Western Europe and found favor first, as is still the case, with the indoor-living sex. It is still among indoor workers that they are most in vogue. But if, as seems likely, alcohol was first adopted by the warriors of savage or semi-savage races as an inspiring or hardening force, it early lost this character with the introduction of strict military discipline on the one hand or of chivalry on the other. Neither the trained soldier of the phalanx and the legion, nor the knight with whom reckless but also intelligent courage was a point of honor, could find any help in intoxication, partial or total; nay, he soon found that while the first excitement of alcohol was fatal to discipline, its subsequent effects were almost as injurious to the persevering, steadfast kind of courage in which he put his pride. Wine or brandy, then, came to be the indulgence of peace and triumph, not of war; wassail followed on victory, sobriety was necessary till the victory was won. But still it has always been on the sterner, fiercer, more energetic races that alcohol, and especially the stronger forms of alcohol, retained their hold. It is to the passive, quiet, reflective temperaments—national or individual, peculiar to classes or to crafts—that tea or coffee, opium or haschisch, substances that calm rather than excite the nerves, have always proved strongly and often dangerously attractive.

Now it may be urged with plausibility, and perhaps with truth, that civilization and intellectual culture, the exchange of out-door for in-door life, the influences that have rendered intelligence and dexterity of more practical value than corporeal strength, tend in some sense and in some measure to Orientalize the most advanced European races. We are not, perhaps, less daring or less enterprising than our fathers; but there is a large and ever increasing class to which strenuous physical exertion is neither habitual nor agreeable. We are unquestionably becoming sedentary; we work much more with our brains, much less with our muscles, than heretofore. With this change has come a decided change of feeling and tastes. We shrink from the fierce excitement, the violent moral stimulants that delighted ruder and less sensitive races and generations. The gladiatorial shows of Rome, the savage sports and public punishments of the Middle Ages, would be simply revolting to the great majority of almost every European nation of to-day; not primarily because as thoughtful Christians we deem them wicked, but because, instinctively, as sensitive men and women in whom imagination and sympathy are strong, we shudder at them as brutal. Prize-fights, bear-baiting, bull-fights have become too rough, too coarse, but above all too exciting; the hideous tragedies of old have ceased to suit the taste at least of our cultivated classes. In one word, our nerves are far too sensitive to crave for strong and violent excitement, moral or physical; it is painful rather than pleasurable. The sobriety of the educated classes is due much less to moral than to social causes. It is not that strong wines and spirits are so much more injurious to us than to our grandsires, nor that we have learned in fifty years to think intoxication sinful; rather we have come to despise it, and to dislike its means, because we have ceased to feel or understand the craving for such violent stimulation, because not merely the reaction but the excitement itself gives more pain than pleasure.

In the case of our American kinsmen climate has very much to do with the matter. A dry, keen, exhilarating air as well as an intense nervous sensibility renders powerful alcoholic stimulants unnecessary, over-exciting, unpleasant as well as injurious. Partly from temperament, a temperament which in itself must be largely the result of climate, partly from the direct influence of their drier, keener atmosphere, American women feel no need of alcohol; American men who do indulge in it, rather as a relief from brain excitement than as an excitant itself, suffer far more than we do from the indulgence. The number of drunkards or hard-drinkers in the older States is, we believe, very much smaller than in England, even at the present day. But the proportion of lunatics made by drink seems to be much larger. In America alone teetotalism has been the serious object of social and legislative coercion. The Maine Liquor Law failed; but it is enforced in garrisons and colleges, while in many States social feeling and sectarian discipline forbid wine and spirits to women and clergymen, and habitual indulgence therein, however moderate, is hardly compatible with a high reputation for religious principle or strict morality. But this case, like that of the early Mahometans, is the case of a people whose climate is unsuited to alcohol; whose very atmosphere is a stimulant.

In a word, the craving of to-day, moral and physical, especially among the cultivated classes, among the brain-workers, among those of the softer sex and of the fruges consumere nati, who are almost entirely relieved from physical labor, is for mild prolonged stimulation, and for stimulation which does not produce a strong reaction; or else for sedatives which will allay the sleepless excitement produced by over-work, or yet oftener, perhaps, by reckless pursuit of pleasure.

It seems, then, not unnatural or improbable that, as tea and coffee have so largely taken the place of beer or light wine as beverages, so narcotics should take the place of stronger alcoholic stimulants. That this has been the case in certain quarters is well known to physicians, and to most of those who have that experience of life in virtue of which it is said, “every man of forty must be a physician or a fool.” Nay, it is difficult to read the newspapers and remain ignorant or doubtful of the fact. We read weekly of men and women poisoned by an over-dose of some favorite sedative, burnt to death, or otherwise fatally injured while insensible from self-administered ether or chloroform. For one fatal case that finds its way into the newspapers there are, of course, twenty fatal in a different sense—fatal, not to life, but to life’s use and happiness—that are never known beyond the family circle, into which they have introduced unspeakable and often almost unlimited sorrow and evil; unlimited, for no one can be sure, few can reasonably hope, that the mischief will be confined to the individual victim of a dangerous craving. That the children of drunkards are often pre-disposed to insanity is notorious; that the children of habitual opium-eaters or narcotists inherit an unmistakable taint, whether in a diseased brain, in diseased cravings, or simply in a will too weak to resist temptation of any kind, is less notorious but equally certain. Of these secondary victims of chloral or opium there are not as yet many; but many fathers and mothers—fathers, perhaps, who for the sake of wives and children have overtaxed their brains till nothing but either the rest which circumstances and family claims forbid, or drugs, will give them the sleep necessary to the continuance of their work; mothers, too commonly, who begin by neglecting their children in the pursuit of pleasure, to end by poisoning their unborn offspring in the struggle to escape the consequences of that pursuit—are preparing untold misery and mischief for a future generation. Happily, narcotism is not the temptation of the young or energetic. It is later in life, when the effect of years of brain excitement of whatever nature begins to tell, and generally after the period in which the greater number of children are born, that men and women give way to this peculiar temptation of the present age.

The immediate danger to themselves is sufficiently alarming, if only it were ever realized in time. The narcotist keeps chloroform or chloral always at hand, forgetful or ignorant that one sure effect of the first dose is to produce a semi-stupor more dangerous than actual somnolence. In that semi-stupor the patient is aware, or fancies that the dose has failed. The pain that has induced a lady to hold a chloroformed handkerchief under her nostrils returns while her will and her judgment are half paralysed. She takes the bottle from the table beside her bed, intending to pour an additional supply on the handkerchief. The unsteady hand perhaps spills a quantity on the sheet, perhaps sinks with the unstoppered bottle under her nostrils; and in a few moments she has inhaled enough utterly to stupefy if not to kill. The vapor, moreover, is inflammable; perhaps it catches the candle by her side; and she is burnt to death while powerless to move. The sleepless brain-worker also feels that his usual dose of chloral has failed to bring sleep; he is not aware how completely it has stupefied the brain, to which it has not given rest. His judgment is gone, so is his steadiness of hand; and, whether intentionally or not, at any rate unconsciously, so far as reasoning and judgment are concerned, he pours out a second and too often a fatal dose. Any one who knows how great is the stupefying power of these drugs, how often they produce a sort of moral coma without paralysing the lower functions of animal or even of mental life, would, one might suppose, at least take care to be in bed before the drug takes effect, and if possible to put it out of reach till next morning. But experience shows how seldom even this obvious and essential precaution is taken.

The cases that end in a death terrible to the family, but probably involving little or no suffering to the victim himself, are by no means the worst. A life poisoned, paralysed, rendered worthless for all the uses of intellectual, rational, we might almost say of human existence, is worse for the sufferer himself and for all around him than a quick and painless death; and for one such death there must be twenty if not a hundred instances of this worst death in life. In nine cases out of ten, probably, the narcotist has been entangled almost insensibly, but incurably, without intention and almost without consciousness of danger. With alcohol this could hardly be the case. No woman, at any rate, could reach the point at which secret indulgence in wine or spirits became a habit and a necessity without warnings, evidences of excess palpable to herself if not to others, that should have terrified and shamed her into self-control, while self-control was yet possible. The hold that opium and other narcotics acquire is at once swifter, more gradual, less revolting and incomparably stronger than that of alcohol. The first indulgence is in some sense legitimate; is almost enforced, either by acute pain or by chronic insomnia. The latter is perhaps the more dangerous. The pain, if it last for weeks, forces recourse to the doctor before the habit has become incurable. Sleeplessness is a more persistent, and to most people a much less alarming thing; and it is moreover one with which the doctors can seldom deal save through the very agents of mischief. Neuralgia, relieved for a time by chloroform or morphia, may be cured by quinine; sleeplessness admits of hardly any cure but such complete change of life as is rarely possible, at least to its working victims. And the narcotist habit once formed, neither pain nor sleeplessness is all that its renunciation would involve. The drunkard, it must be remembered, gets drunk, as a rule, but occasionally. Save in the last stages of dipsomania, he can do, if not without drink, yet without intoxicating quantities of drink, for days together. The narcotist who attempts to go for a whole day without his accustomed dose, suffers in twenty-four hours far more cruelly than the drunkard deprived of alcohol in as many days. The effect upon the stomach and other organs, upon the nerves as well as on the brain, is one of indescribable, unspeakable discomfort amounting to torture; a disorder of the digestive system more trying than sea-sickness, a disorganization of the nerves which after some hours of unspeakable misery culminates in convulsive twitchings, in mental and physical distress, simply indescribable to those who have not felt it. Where attempts have been made forcibly and suddenly to withhold the accustomed sedative, they have not unfrequently ended within a few days in madness or death. In other cases the victim has sought and obtained relief by efforts and through hardships which, in his or her best days, would have seemed impossible or unendurable. One woman thus restrained escaped in a dÉshabille from her bed-room on a winter night of Arctic severity; ran for miles through the snow, and was fortunate enough to find a chemist who knew something of the fearful effect of such privation, and had the sense and courage to give in adequate quantity the poison that had now become the first necessary of life. In a word, narcotics, one and all, are, to those who have once fallen under their power, tyrants whose hold can hardly ever be shaken off, which punish rebellion with the rack, and with all those devices of torture which mediÆval and ecclesiastical cruelty found even more terrible than the rack itself; while the most absolute submission is rewarded with sufferings only less unendurable than the punishment of revolt. De Quincey’s dreams under the influence of opium were to the tortures of resistance what the highest circle of purgatory may be to the lowest pit of the Inferno. But any reader who knows what nightmare is would think such tortures of the imagination, so vividly realized by a consciousness apparently intensified rather than impaired by slumber, a sufficient penalty for almost any human sin.

Chloral, bromide of potash, chloroform, henbane, and their various combinations and substitutes are, however, by their very natures medicines and no more. They are taken in the first instance as such; at worst as medicinal equivalents for a quantity of alcohol which women are afraid to take or unable to obtain, much more commonly as medicines originally useful, mischievous only because the system has been accustomed to depend on and cannot dispense with them. Their effects at best are negatively, not actively, pleasurable. They relieve pain or insomnia, or the craving which they themselves have created; but their victims would, if they could, gladly be released from their tyranny. Their character, moreover, is if not immediately yet very rapidly perceptible. Very few can have used them for six months without becoming more or less alarmed by the consequences. The minority, for whom they are mere substitutes for alcohol, resort to them only when the system has already been poisoned, the habits incurably vitiated. With opium the case is different. In those which may be called its native countries, it is not a medicine but a stimulant or sedative, used for the most part in much greater moderation but in the same manner as wine or spirits among ourselves; as an indulgence pleasurable and innocent, if not actually desirable in itself. It suits the climates and temperaments to which the heating, exciting influence of alcohol is wholly unsuitable. It is, moreover, incompatible with the free use of the latter, a thing which may be said in some sense of most narcotics. Taken up by persons not yet addicted to intemperance, chloral and similar drugs operate to discourage the use, or at least the free use, of wine or spirits by intensifying their effect to a serious and generally an unpleasant degree. But it does not appear that they act, like opium, to indispose the system for alcohol. To the opium-eater, as a rule, the exciting stimulus of alcohol, counteracting the quiet, dreamy influence of his favorite drug, is decidedly obnoxious; the action of chloral much more resembles that of the more stupefying and powerful spirits. A drunkard desirous to abandon his favorite vice, and reckless or incredulous of the possibility that the remedy may be worse than the disease, would probably find in opium the most powerful and effectual assistance and support to which he could have recourse. It has moreover a strong tendency to diminish the appetite for food, so much so that both in the East and in Europe severe privation tends to encourage and diffuse its use.

Its peculiar danger, however, lies in the nature of the pleasure, and the remoteness of the pain and mischief which attend its use. Its effect on different constitutions and at different periods of life is exceedingly different. As De Quincey remarks, it is not essentially and primarily narcotic. It does not necessarily, immediately, or always produce sleep. Some fortunate temperaments reject it in all forms whatever. With these it produces immediate or speedy nausea, and consequent repugnance. But its most universal effect is the diffusion of comfort, quiet, calm, conscious repose, a general sensation of physical and mental ease throughout the system; not followed necessarily or generally by acute reaction, or even by depression. De Quincey’s earlier experience accords with that of most of those to whom opium is in some sense suited, to whom alone it is likely to become a dangerous temptation. Used once in a fortnight, or even once a week, it gives several hours of placid enjoyment, and if taken with some mild aperient and followed next morning by a cup of strong coffee, it generally gives a quiet night’s rest, entailing no further penalty than a certain not unpleasant lassitude on the morrow. A working-man, for instance, might take it every Saturday night for twenty years without other effect than a decided aversion to the public-house on Sunday, if he could but resist the temptation to take it oftener. Again, till it loses its power by constant use it is in many cases the surest and pleasantest of all anÆsthetics; it relieves all neuralgic pains, tooth-ache and ear-ache for example, and puts, especially in combination with brandy, a quick and sure if by no means a wholesome check on the milder forms of diarrhoea.

In this connection one danger peculiar to itself deserves especial notice. Other narcotics are seldom given or sold save under their own names; and if administered in combination, in quack medicine or unexplained prescriptions, their effect betrays itself. Opium forms the basis of innumerable remedies and very effective remedies, sold under titles altogether reassuring and misleading. Nearly all soothing-syrups and powders for example—“mother’s blessings” and infant’s curses—are really opiates. These are known or suspected by most well-informed people. What is less generally known is that nine in ten of the popular remedies for catarrh, bronchitis, cough, cold and asthma are also opiates. So powerful indeed is the effect of opium upon the lining membrane of the lungs and air passages, so difficult is it to find an effective substitute, that the efficacy, at least the certain and rapid efficacy, of any specific remedy for cold whose exact nature is not known affords strong ground for suspecting the presence of opium. Many chemists are culpably, almost criminally, reckless; and not a few culpably ignorant in this matter. An experienced man bought from a fashionable West-end shop a box of cough lozenges, pleasant to the taste and relieving a severe cough with wonderful rapidity. Familiar with the influence of opium on the stomach and spirits, he was sure before he had sucked half-a-dozen of the lozenges that he had taken a dose powerful enough to affect his accustomed system, and strong enough to poison a child, and do serious harm to a sensitive adult. Yet the lozenges were sold without warning or indication of their character; few people would have taken any special precaution to keep them out of the way of children, and the box, falling into the hands of a heedless or disobedient child, might have poisoned a whole nursery.

Another personal experience may serve to dispel the popular delusion that opium is necessarily or generally a stupefying agent. A mismanaged minor operation exposed two sensitive nerves, producing an intolerable hyperÆsthesia and a nervous terror which rendered surgical relief for the time impossible, and endurance utterly beyond human power. For a fortnight or more the patient was never free from agony save when the nerves of sensation were practically paralysed by opium. During that fortnight he took up for the first time, and thoroughly mastered, as a college examination shortly afterwards proved, Mill’s Principles of Political Economy, a work not merely taxing to the uttermost the natural faculties of nineteen, but demanding beyond any other steady persistent coherence and lucidity of thought. The patient affirmed that never had his mind been clearer, his power of concentration greater, his receptive faculties more perfect or his memory more tenacious. That the drug had in no wise impaired the intellectual, however it might have quelled the muscular or nervous energies, seems obvious. Yet at that time the patient was ignorant of the two antidotes above mentioned; and neither coffee nor aperient medicine qualified or mitigated the influence of the opiates; an influence strong enough to quell for some twenty-two hours out of the twenty-four an acute and terrible nervous torture.

After the use of a fortnight or a month—especially when used legitimately to relieve pain and not to procure pleasure—the entire abandonment of opium may be easily accomplished in the course of two or three days. The pain or the disease it is used to overcome carries off, so to speak, or diverts in great measure the injurious influence of the drug; as a person suffering from diarrhoea, snakebite, or other cause of intense lowering of physical and nervous power, may take with impunity a dose of brandy which in health would certainly intoxicate him. But after six months’ or a year’s daily use or abuse, only the strongest and sternest resolution can overcome or shake off the tyranny of opium, and then only at a price of suffering and misery, of physical and mental torture such as only those who have known it can conceive.

It would be as foolish to depreciate the value as to underrate the danger of this, the most powerful and in many respects the safest of anÆsthetics. Nothing else can do what opium can to relieve chronic, persistent, incurable nervous pain, to give sleep when sleeplessness is produced by suffering. The more potent anÆsthetics, like chloroform, are applicable only to brief intense tortures, whose period can be foreseen or determined—to produce insensibility during an operation, or to mitigate the pangs of child-birth. Opium can relieve incurable chronic pain that would otherwise render life intolerable, and perhaps drive the sufferer to suicide; and this, if moderation be observed, and the necessary correctives employed, without impairing, as other narcotics would, the intellectual faculties. It is, moreover, as aforesaid, the quickest and surest cure for bronchial affections of every kind, and might not impossibly, as De Quincey thought, if used in time and with sufficient decision, prolong a life otherwise doomed, if it could not actually cure phthisis or consumption after the formation of tubercle has once begun. But its legitimate use is limited to three cases. It can relieve temporary neuralgic pain when cure would be slow, or while awaiting a curative operation. One peculiarity of neuralgic pain is its tendency to perpetuate itself. The nerves continue to thrill and throb because worn out by pain. Give them, through whatever agency, a brief period of rest, and it may well happen that, the temporary cause removed, the pain will not return. Secondly, opium is the one anÆsthetic agency available to mitigate incurable and intolerable suffering. Not only can it render endurable a life that must otherwise be one continuous torture, till torture hastens death; but it may in many cases render that life serviceable as well as endurable. De Quincey gives the instance of a surgeon, suffering under incurable disease of an intolerably painful kind, who owed the power of steady professional work for more than twenty years to the constant use of opium in enormous quantities. Finally, when a working life draws near its natural close, when old age is harassed by the nervous consequences of protracted over-work or over-strain such as is often almost inseparable from the anxieties of business—the severe taxation of the mental powers by professional or literary labor—opium, given habitually in small quantities and under careful medical direction, often does what wine effects with less certainty and safety; gives rest and repose, calms an irritability of nerve and temper more trying to the patient himself than to those around him, and renders the last decade of a useful and honorable life much more comfortable, and no wit less useful or honorable, than it might otherwise have been.

But except as a relief in incurable disease, or in that most incurable of all diseases, old age, the continual or prolonged use of opium is always dangerous and nearly always fatal. It impairs the will; not infrequently it exercises a directly, visibly, unmistakably deteriorating influence upon the moral nature. There is nothing strange in this to those who know how an accidental injury to the skull may impair or pervert the moral no less than the intellectual powers. That moral is hardly a less common or less distinctive disease than mental insanity, that the conscience as well as the intellect of the drunkard is distorted and weakened, no physiologist doubts. Opium has a similar power, but exerts it with characteristic slowness of action. The demoralization of the narcotist is not, like that of the drunkard, rapid, violent, and palpable; but gradual, insidious, perceptible only to close observers or near and intimate friends. In nine cases out of ten, moreover, opium ultimately and certainly poisons the whole vital system. The patient loses physical and mental energy, courage, and enterprise; shrinks from exertion of every kind, dreads the labor of a walk, the trouble of writing a letter, dreads still more intensely any effort that calls for moral courage, flinches from a scene, a quarrel, a social or domestic conflict, becomes at last selfish, shameless, weak, useless, miserable to the last degree.

But this, like every other effect of opium, is in some measure uncertain; and hence arises one of its subtlest dangers. De Quincey would seem to have been less susceptible than most men to the worst influences of his favorite drug, seeing what work, excellent in quality as well as considerable in quantity he achieved after he had become a confirmed opium-eater. It took, no doubt, a tenfold greater amount of opium to reduce him to intellectual impotence than would suffice to destroy the minds of nine brain-workers in ten. But his own story clearly reveals how completely the enormous doses to which he had recourse at last overpowered a mind exceptionally energetic, and a temperament exceptionally capable of assimilating, perhaps, rather than resisting the power of opium. Here and there we find a constitution upon which it exerts few or none of its characteristic effects. As a few cannot take it at all, so a few can take it with apparent impunity. With them it will relieve pain and will not paralyse the nerves, will quell excitement without affecting mental energy; nay, while leaving physical activity little more impaired than age and temperament alone might have impaired it. Here and there we may find a confirmed opium-eater capable of taking and enjoying active exercise—a fairly fearless rider, a lover of nature tempted by taste, or it may be by restlessness, to walks beyond his muscular strength; with vivid imagination well under his own control; in whom even the will seems but little weakened, whose dread of pain and flinching from danger are not more marked after twenty years spent under the influence of opium than when they first drove him to its use. Such cases are, of course, wholly exceptional; but their very existence is a danger to others, misleads them into the idea that they may dally with the tempter, may profit by its pleasure-giving and pain-quelling powers without falling under its yoke, or may fall under that yoke and find it a light one. I doubt, however, whether the most fortunate of its victims would encourage the latter idea; whether there be any opium-eater who would not give a limb never to have known what opium can do to spare suffering, to give strength for protracted exertion, if he had never known what slavery to its influence means.

Dread of pain, dislike of excitement and worry, impatience of suffering and discomfort, of irritation, and sleeplessness, are all strong and increasingly-marked characteristics of our highly artificial life and perhaps almost overstrained civilization. Nature knows no influence that can relieve worry, mitigate pain, charm away restlessness, discomfort, and even sleeplessness, as opium can. Alcohol is at once too stupefying and too exciting for the tastes and temperaments that belong to cultivated natures and highly-developed brains. Beer suits the sluggish laborer, or the energetic navvy when his work is done, and his system, like that of a Scandinavian Viking or Scythian warrior in his hours of repose, craves first exhilaration and then stupid, thoughtless contentment. Wine suits less active and more passionate races, to whom excitement is an unmixed pleasure; brandy those who crave for stronger excitement to stimulate less susceptible nerves. But the physical stimulants of our fathers and grandfathers, as the moral excitements of remoter times, are far too violent for our generation. Champagne has succeeded port and sherry as the favorite wine of those who can afford it, being the lightest of all; and time was, not so long ago, when medical men were accused of recommending champagne with somewhat careless facility to those whose nerves, worn out by unhealthy pursuit of pleasure, by unnatural hours and unwholesome excitement, might have been effectually though more gradually restored by a change which to most of them at least was possible; by life in the country rather than in London, by the fresh air of the early morning instead of that of midnight in over-heated gas-lighted rooms and a poisoned atmosphere. There is a danger lest, as even champagne has proved too much of a stimulant and too little of a sedative, narcotics should take its place. The doctors will hardly recommend opium, but their patients, obliged for one reason or another to forego wine, might be driven upon it.

As aforesaid, the craving for stimulation or tranquillization of the brain—in one word, for that whole class of nerve-agents to which tea, opium, and brandy alike belong—is so universal, has so prevailed in all ages, races and climates, that it must be considered, if not originally natural, yet as by this time an ingrained, all but ineradicable, human appetite. To baffle such an appetite by any coercive means, by domestic, social or legislative penalties, has ever proved impossible. Deprive it of its gratification in one form, and it is impelled or forced to find a substitute; and finds it, as all strong human cravings have ever found some kind of satisfaction. And here lies one of the worst, most certain and yet least considered dangers of the legislation eagerly demanded by a constantly increasing party. Maine liquor laws, prohibition, local option, every measure that threatens to deprive of their favorite stimulant those who are not willing or have not the resolve to abandon it, would probably fail in their primary object. If they succeeded in that, they would, in a majority of instances, force the drinker, not to be content with water or even with tea, but to find a subtler substitute of lesser bulk, more easily obtained and concealed. Opium is the most obvious, and, among sedatives powerful enough to be substituted for wine or spirits, the least mischievous resource. And opium, once adopted as a substitute for alcohol, would take hold with far greater tenacity, and its use would spread with terrible rapidity, because its evil influence is so subtle, so slowly perceptible; and because, if used in moderation and with fitting precautions, its worst effects may not be felt for many years; because women could use it without detection, and men without alarm or discredit. This peril is one of which wiser men than Sir Wilfrid Lawson will not make light, but which too many comparatively rational advocates of total abstinence seem to have totally overlooked. Without underrating the frightful evils of intoxication, its baneful influence upon the individual, upon large classes, and upon the country as a whole, no one who knows them both can doubt that narcotism is the more dangerous and more destructive habit. The opiatist will not brawl in the street, will not beat his wife or maltreat his children; but he is rendered as a rule, even more rapidly and certainly than the drunkard, a useless member of society, a worthless citizen, an indifferent husband, helpless as the bread-winner, impotent as the master and ruler of a household. And opium, to the same temperaments and to many others, is quite as seductive as alcohol; far more poisonous, and incomparably more difficult to shake off when once its tyranny has been established. To forbid it, as some have proposed to forbid the sale or manufacture of beer, wine, and spirits, is impossible; to exclude it from the country is out of the question; its legitimate uses are too important, and no restrictions whatever can put it out of the reach of those who desire it. Silks, spirits, tobacco were smuggled as long as it paid to smuggle them; opium, an article of incomparably less bulk and incomparably greater value, would bring still larger profit to the importer; while the customer would not merely be attracted by cheapness or fashion, but impelled by the most imperious and irresistible of acquired cravings. Any man could smuggle through any barriers enough to satisfy his appetite for a year, enough to poison a whole battalion. That opium can become the favorite indulgence with numerous classes, and apparently with a whole people, the experience of more than one Eastern nation clearly shows. As the Oriental tea and coffee have to so large an extent superseded beer as the daily drink of men as well as women and children, so opium is calculated under favoring circumstances to replace wine and spirits as a stimulant. It might well do so even while the competition was open. Every penalty placed on the use of wine or brandy is a premium on that of opium.

De Quincey is not the only opium-eater who has given his experience to the world. It is evident that the practice is spreading in America, and the records published by its victims are as terrible as the worst descriptions of the drunkard’s misery or even as the horrors of delirium tremens. It is noteworthy, however, how little any of these seem to know of other experiences than their own—for instance, of the numerous forms and methods in which the drug can be and is administered. Opium—the solidified juice of the poppy—is the natural product from which laudanum, the spirituous tincture of opium, and all the various forms of morphia, which may be called the chemical extract, the essential principle of opium, are obtained. Morphia, again, is sold by chemists and exhibited by doctors in many forms, the principal of which are the acetate, the sulphate and the muriate of morphia—the substance itself combined with acetic, sulphuric, or hydrochloric acid. Of these last the muriate is, we believe, the safest, the acetate and in a lesser degree the sulphate having more of the pleasurable, sedative, seductive influence of opium in proportion to their pain-quelling power. They act, in some way, more powerfully upon the spirits while exerting the same anÆsthetic influence, and the injurious effects of each dose are more marked and less easily counteracted. Laudanum, containing proof spirit as well as morphine, and through the proof spirit diffusing the narcotic influence more rapidly and affecting the brain more quickly and decidedly, is perhaps the worst vehicle through which the essential drug can be taken. Again, morphine, in its liquid forms can be injected under the skin; as solid opium it can be smoked or eaten, as morphia it can be swallowed or injected. Of all modes of administration—speaking, of course, of the self-administered abuse, not of the strict medical use of the drug—subcutaneous injection is the worst. It acts the most speedily and apparently the most pleasurably; it passes off the most rapidly, and tempts, therefore the most frequent, re-application. Apart, moreover, from the poisonous influence itself, this mode of application has injurious effects of its own; produces callosities and sores of a painful and revolting character. Smoking seems to be the most stupefying manner in which solid opium can be consumed, the one which acts most powerfully and injuriously upon the brain. But opium-smoking is hardly likely to take a strong hold on English or European taste. A piece of opium no larger than a pea, chopped up and mixed with a large bowlful of tobacco, produces on the veteran tobacco-smoker a nauseating effect powerfully recalling that of the first pipe of his boyhood; while its flavor is incomparably more disagreeable to the palate accustomed to the best havanas or the worst shag or bird’s-eye than these were to the unvitiated taste. It is probable that the Englishman who makes his first acquaintance with opium in this form will be revolted rather than tempted, unless indeed the pipe be used to relieve a pain so intolerable that the nauseousness of the remedy is disregarded. Morphia in all its forms, liquid or solid, has a thoroughly unpleasant bitterness, but neither the nauseous taste of the pipe nor the intensely disgusting flavor of laudanum, a flavor so revolting to the unaccustomed palate that only when largely diluted by water can it possibly be swallowed. On the whole, the muriate, dissolved in a quantity of water large enough to render each drop the equivalent of a drop of laudanum, is probably the safest, and should be swallowed rather than injected. But rather than swallow even this, a wise man, unless more confident in his own constancy and self-command than wise men are wont to be, had better endure any temporary pain that nature may inflict or any remedial operation that surgery can offer.—Contemporary Review.