THE POPPY. ( Papaver somniferum L. )

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DR. ALBERT SCHNEIDER,
Northwestern University School of Pharmacy.

Sleep hath forsook and given me o'er
To death's benumbing opium as my only cure.
Milton, S. A. l. 630.

THE opium-yielding plant or poppy is an herb about three feet in height; stem of a pale green color covered with a bloom. Branches are spreading, with large, simple, lobed or incised leaves. The flowers are solitary, few in number, quite large and showy. The four large petals are white or a pale pink color in the wild-growing plants. The fruit is a large capsule, one to three inches in diameter, of a depressed globular form. The seeds are small and very numerous, filling the compartments of the capsule. In spite of the general attractiveness of the plant, the size of the flowers and the delicate coloring of its petals, it is not a favorite at close range because of a heavy, nauseating odor which emanates from all parts of the plant, the flowers in particular. The petals furthermore have only a very temporary existence, dropping off at the slightest touch.

The wild ancestor of our familiar garden poppy is supposed to be a native of Corsica, Cyprus, and the Peloponnesian islands. At the present time it is extensively cultivated everywhere, both as an ornamental plant and for its seeds, pods, and yield of opium. It has proven a great nuisance as a weed in the grain fields of England, India, and other countries—something like mustard in the oat fields of the central states. There are a number of forms or varieties of the cultivated poppy. The red poppy, corn poppy, or rose poppy (Papaver Rhoeas) is very abundant in southern and central Europe and in western Asia. It has deep red or scarlet petals and is a very showy plant. The long headed poppy (P. dubium) has smaller flowers of a lighter red color and elongated capsules, hence the name. The Oriental poppy (P. orientale) has very large, deep red flowers on a tall flower-stalk.

Various plants belonging to other genera of the poppy-family (PapaveraceÆ) are designated as poppy. The California poppy (Eschscholzia Californica) is a very common garden plant. It has showy yellow flowers and much divided leaves. Horn poppy (Glaucium luteum) is a rather small seaside plant, with long curved pods and solitary yellow flowers. The Mexican prickly poppy (Argemone Mexicana) is widely distributed. The pods and leaves are prickly, flowers yellow or white; the seeds yield an oil which is used as a cathartic. Spatling or frothy poppy (Silene inflata) is so-called because when punctured by insects or otherwise it emits a spittle-like froth. Tree poppy (Dendromecon rigidum) is a shrub six to eight feet high, with large, bright yellow flowers. Welsh poppy (Mecanopsis cambrica), a plant found in the wooded and rocky parts of western Europe, has sulphur-yellow flowers and is cultivated for ornament.

The use and cultivation of the poppy dates from very remote times. The plant was well known in the time of the eminent Greek poet Homer, who speaks of the poppy juice as a dispeller of sorrows (Odyssey, IV. l. 220). According to Plinius the word poppy (Papaver) is derived from papa, meaning pap, the standard food of infants, because poppy juice was added to it for the purpose of inducing sleep. The ending ver is from verum, meaning true; that is, this food was the true sleep-producing substance. Opium, the inspissated juice of the poppy pods, was apparently not known in the time of Hippocrates, only the freshly expressed juice being used. It is through Diocles Karystius (350 B. C.) that we obtain the first detailed information regarding the use of opium. Nicandros (150 B. C.) refers to the dangerous effects produced by this drug. Scribonius Largus, Dioscorides, Celsus, and Plinius gave us the first reports regarding the origin, production, and adulteration of opium. Plinius mentions the method of incising the capsules. The Arabians are said to have introduced opium into India. It appeared in Europe during the middle ages, but was apparently in little demand. It was much more favorably received in the Orient. In 1500 it constituted one of the most important export articles of Calcutta. India supplied China with large quantities of opium, at first only for medicinal purposes. It is said that the Chinese acquired the habit of smoking opium about the middle of the seventeenth century, and since then it has ever been the favorite manner of consuming it.

The poppy is cultivated in temperate and tropical countries. The opium yield of plants grown in temperate climates is, however, much less than that of the subtropical and tropical countries, though the quality is about the same. There are large poppy plantations in India, China, Asia Minor, Persia, and Turkey. As already indicated, the white-flowered variety is quite generally cultivated because it yields the most opium.

The plants are grown from seed, and it is customary, in tropical countries, to sow several crops each season to insure against failure and that collecting may be less interrupted. Plants of the spring sowing flower in July. The pods do not all mature at the same time; this, coupled with the sowing of several crops at intervals of four to six months, makes the work of collecting almost continuous. Before the pods are fully developed they are incised horizontally or vertically with a knife. Generally a special knife with two and three parallel blades is used. The blades of the knife are repeatedly moistened with saliva to prevent the poppy juice from adhering to them. The incisions must not extend through the walls of the capsule, as some of the juice would escape into the interior and be lost. As soon as the incisions are made a milky sap exudes, which gradually thickens, due to the evaporation of moisture, and becomes darker in color. The following day the sticky, now dark-brown juice, is scraped off and smeared on a poppy leaf held in the left hand; more and more juice is added until a goodly sized lump is collected. These sticky, ill-smelling masses of opium are now placed in a shaded place to dry. The entire process of incising and collecting as carried on by the Orientals is exceedingly uncleanly. To the nasty habit of moistening the knife-blade with saliva is supplemented the filth of unwashed hands and the sand and dirt of the poppy leaves, which are added from time to time to form a new support for the juice as it is removed from the knife. In scraping the gum considerable epidermal tissue is also included. Each lump of gum opium contains therefore a mixture of spittle, the filth of dirty hands, poppy leaves, sand, and dust. In addition to that many collectors adulterate the gum opium with a great variety of substances. Dioscorides mentions the fact that even in those remote times adulteration of opium was practiced, such substances as lard, syrup, juice of lactuca, and glaucium being added. Modern collectors and dealers adulterate opium with sand, pebbles, clay, lead, flour, starch, licorice, chicory, gum arabic and other gums, figs, pounded poppy capsules, an excessive quantity of poppy leaves and other leaves, etc. After collecting and drying the peasants carry the gum opium to the market-places, where they are met by the buyers and merchants, who inspect the wares and fix a price very advantageous to themselves.

The present trade in opium is something enormous, especially in India, China, and Asia Minor. To the credit of the Chinese and the discredit of the English it must be said that in 1793 the former strenuously objected to the introduction of opium traffic by the latter. This opposition by the Chinese government culminated in the "Opium War," which led to the treaty of Nanking in 1842, giving the English the authority to introduce opium into China as a staple article of commerce. The reason that Chinese officials objected to the introduction of opium was because they recognized the fact that the inhabitants very readily acquired the habit of smoking opium. In spite of the most severe government edicts the habit spread very rapidly after the treaty referred to.

Gum opium contains active principles (alkaloids), to which it owes its peculiar stimulating, soporific, and pain-relieving powers. Of these alkaloids, of which there are about nineteen, morphine and codeine are undoubtedly the most important. The properties of gum opium represent therefore the collective properties of all of the alkaloids and are similar to the properties of the predominating alkaloids just mentioned.

Physicians generally agree that opium is the most important of medicines. Properly used it is certainly a great boon to mankind, for which there is no substitute, but, like all great blessings, it has its abuses. It is the most effective remedy for the relief of pains and spasms of all kinds. It will produce calm and sleep where everything else has failed. It finds a use in all diseases and ailments accompanied by severe pain, in delirium, rheumatic and neuralgic troubles, in dysentery, etc. It may be applied externally to abraded surfaces, to ulcers and inflamed tissues for the relief of pain. The value of opium does not lie so much in its direct curative powers as in its sedative and quieting effects upon diseased organs, which tends to hasten or bring about the healing or recuperating process. In some diseases the physician refrains from giving opium, as in fully developed pneumonia, since the quieting effect would diminish the efforts on the part of the patient to get rid of the inflammatory products accumulating in the air vesicles and finer bronchial tubes. In fact, the soothing effect is too often mistaken for a curative effect and the patient is neglected. The Roman habit of feeding children pap mixed with poppy juice was a pernicious one. Many modern mothers give their sick and crying infants "soothing syrups," most, if not all, of which contain opium in some form, as tincture of opium and paregoric. Too often the poor, overworked mother, who cannot afford to consult a physician, will purchase a bottle of "soothing syrup" or "cough remedy" for her child because she knows it produces a quieting effect, which is mistaken for a cure, when in reality the incipient symptoms are only masked. Only a reliable physician should be permitted to prescribe opium in any form.

The harm done through the use of opium by the ignorant, abetted by the "inventors," manufacturers and sellers of the "soothing syrups" and "cough remedies," is insignificant as compared with the harm resulting from the opium habit, which is acquired in various ways. For instance, a patient learns that the opium given him relieves pain and produces a feeling of well-being; hence, even after recovering, he returns to the use of the solace of his sickness when he suffers mental or physical pain, and in time the habit is acquired. The scholar knowing its properties makes use of it to deaden pain and to dispel imaginary or real mental troubles. Any and all classes may acquire the opium habit, but the majority of opium-eaters are from the lower and middle classes. As with other vices, the predisposing cause is a lack of moral stamina. Women are more addicted to the habit than men. After the habit is once established it is practically impossible to break away from it.

Under the influence of the narcotic the opium-eater becomes mentally active, hilarious, and even brilliant. Thoughts flow easily and freely. In time the patient loses all sense of moral obligation; he boasts and lies apparently without the least trouble of conscience. As soon as the effects of the drug pass away he becomes gloomy, morose, despondent, and he will resort to any measure to obtain a fresh supply. The dose of the drug must be increased continually, until finally quantities are taken which would prove fatal to several persons not addicted to its use.

Opium victims take the narcotic in various ways. The Chinese and Orientals in general prefer to smoke the crude opium in special pipes. Europeans and Americans usually take it internally in the form of the tincture or laudanum, paregoric or the powder of the sulphate of morphine or codeine. Frequently a solution of morphine is injected under the skin by means of a hypodermic syringe. No matter how it is taken the effects are about the same.

The treatment of the opium habit consists principally in the gradual withdrawal of the supply of the drug and strengthening the weakened system by proper exercise and diet, but, as indicated, the habit, if once fully established, is very difficult to cure. While, as stated, most of the opium-eaters belong to the poorer and middle classes, there are a number from the wealthy idle classes and not a few from professional classes who are slaves to the habit. The brilliant and gifted De Quincey was addicted to this habit and recorded his experience in his "Confessions of an Opium-Eater."

The capsules and seeds of the opium plant are also used. The capsules are collected at maturity, but while yet green, usually during the month of July. They are broken and dried in a shaded, well-ventilated place, and finally in a moderately warm place; they are then broken in still smaller pieces, the seeds shaken out and the capsule fragments placed in well-sealed glass or tin receivers. The seeds, which are known as maw seeds, are collected at maturity and placed in wooden boxes. The seeds yield an oil which is used much like sweet oil; artists also use it in mixing colors.


                                                                                                                                                                                                                                                                                                           

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