In reply to your inquiries, I can give you my experience in a few words. I can offer no opinion as to the effects of tobacco, as I have never been a smoker. My experience of many years favours the view that moderation in food and drink is the great secret of physical health, mental activity and endurance. On several occasions while working twelve and fourteen hours a day, I tried total abstinence, but I found myself dyspeptic and stupid, and was obliged to resume my accustomed potations. I have found that any unusual amount of alcohol, while stimulating mental activity for a time, soon produced lassitude and sleepiness.

T. ERSKINE MAY.
February 23, 1882.