With regard to the use of alcohol and tobacco, I do not think any general rule can be laid down. Some powerful thinkers are very considerable smokers, while other powerful thinkers would have been damaged, if not ruined, by the practice. A similar remark applies in the case of alcohol. In my opinion, the man is happiest who is so organised as to be able to dispense with the use of both.

JOHN TYNDALL.
Feb. 14, 1882.

MR. IVAN TOURGUENEFF.

In answer to your enquiry I have to state that I have no personal experience of the influence of tobacco and alcohol on the mind, as I do not smoke or use alcoholic drinks. My observations on other people lead me to the conclusion that tobacco is generally a bad thing, and that alcohol taken in very small quantities can produce a good effect in some cases of constitutional debility.

Iv. TOURGUENEFF.
March 14, 1882.