"The stimulating action on the brain of quantities far short of intoxicating, is accompanied with a paralysing action which seems most rapidly and powerfully to involve the higher faculties. Mental work may seem to be rendered more easy, but ease is gained at the expense of quality. The editor of a newspaper will tell you that, if he has been dining out, he cannot with confidence write a leading article until he has allowed sufficient time to elapse from the effect of the wine he has drunk, in moderation, to pass away; and even the novelist, whose brain-work is in the regions of imagination, will relate a similar experience…. In a person accustomed to the use of tobacco the intellectual work is difficult when smoking cannot be indulged in, the mind cannot easily be concentrated on a subject, and unrest is produced—but this disappears when recourse is had to smoking; and probably some of its reputation as a soothing agent has on this account been acquired. The circulation is also a little excited, and no doubt this assists in rendering brain work more easy. In a short time, however, the circulation is slightly depressed, the pulse becoming smaller; and this may assist in producing the soothing effect generally experienced."

The Use and Abuse of Alcoholic Stimulants and Tobacco. 1881