M. Haffkine, of cholera inoculation fame, has commenced to inoculate against the plague under the same principles on which his inoculation against cholera is based. By injecting into the body an attenuated virus of plague, a very mild attack is produced, which in people inoculated has proved harmless. This mild attack, it is thought, would protect the system from more potent forms of the poisonous germs. The inoculation for plague is still in its experimental stage, and cannot, for obvious reasons, be applied to a large population. Medical attendants, nurses and others who, by call of duty, have to constantly come in contact with plague patients may, however, take advantage of this means of protection, which, in the hands of M. Haffkine, may yield good results. Yersin also claims for his serum prophylactic value. In this and all other matters connected with bacteriology, such as germs, sero-therapeutics, &c., the medical profession now-a-days receives a good deal of satirical remarks from sceptical lay public. It is natural that it should be so, for the science of bacteriology is still in its infancy, and many of its practical applications are still in their experimental stage. But undoubtedly the science is advancing, and by its aid we are now better able to understand diseases and their nature. Many facts have been demonstrated and proved with precision. What is disbelieved to-day, may, however, be believed tomorrow, for, with all human attempt to reveal secrets of nature, such is the case. Readers of Smollet’s Roderick Random may remember how in the Surgeon’s Hall one of the examiners said:—“I affirm that all wounds of the intestine whether great or small are mortal.” Now, however, if a man dies of a wound of the intestine, the unfortunate doctor in whose hand such a casualty takes place runs great risk of being charged with malpraxÈs.