"MY BOOK" CONTINUED.
Abernethy, in impressing any anatomical fact, would sometimes say that we carried about with us in our own bodies excellent means of refreshing our impressions on many points of anatomy; but we may say this in a much more extensive sense with regard to the interpretation of that for which anatomy is alone useful—namely, the uses or functions of the body. It would be very possible for any observant person, who was moderately versed in the ordinary principles of correct reasoning, to detect many defects in medical investigations and practice; in the correction of which many of Abernethy's practical contributions consisted; but the mind, restlessly impatient to arrive at conclusions, often overlooks the most important facts, and deduces inferences directly from the evidence of the eye or other senses, without submitting it to such test as the intellectual faculty can alone supply. Nothing can exceed the mischief of this in serious matters, nor the absurdity of it, when we think awhile. We should hardly refrain from laughter if we saw a man try to see with the point of his nose, or endeavour to examine the odour of a rose by his ear, or to listen with his eye; yet this is not a whit more absurd than to try to deduce conclusions from the impressions furnished by the eye, which can alone be afforded by the rational faculty. Nothing is more common than this sort It is curious, however, to observe how the real business of the human mind is shadowed forth in the very abuses of its powers; nothing so bad but it is charged with a certain quantity of good; no error so great but carries with it the element of its own correction. The mind in its greatest aberrations is followed by the shadow of its real duty, which as it were waits on the time when clearer views shall burst on it. Nothing shows the real tendencies of mind more than its restless desire to arrive at some conclusion, some tangible evidence of its highest functions. It is the impulse of this instinct—the ungoverned abuse of a high faculty, impatient for illegitimate fruition—which lies at the bottom of much false reasoning, and which blinds men, even of great power, to obstacles which are luminously evident to the most ordinary capacity. Important as the next series of illustrations cited by Abernethy are, the conclusions he deduced from them were the necessary sequences of clear and correct reasoning on familiar and established facts. The illustrations in question were those afforded by various cases of injuries of the head, in which certain consequences, however exceptional they may be, are too commonly referred to the abstract nature of the injury. We see that a man has a blow, we see that he does not recover in the usual way in which we have known many others to recover; but we do not, perhaps, There can now be few observant surgeons who have not met with cases in illustration of these circumstances; and yet I know not to whom the perusal of Mr. Abernethy's cases might not be useful. It is not without regret that I forego transcribing at least one of them; forgetful how impossible it is to do Abernethy full justice in a work intended for all readers. In his "Book," the cases in question begin at page 97, and occupy but a few pages. The next class of cases, from which Abernethy illustrates the prevailing influence of the digestive organs, receives additional importance from the imperfect manner in which the phenomena have been interpreted in a vast variety of diseases; like small-pox and others, ascribed to the action of particular poisons. We may possibly have an opportunity of saying something more on this subject; but we may remark that when any disease has been presented to the physician or surgeon, supposed to be the result of specific poisons, it is just the last case in which any special attention is paid to the digestive organs. Now Abernethy observed In the meantime, we may refer to the illustration afforded by small-pox of the remarkable influence of the digestive organs in diseases called specific. We adduce this, because it is one which is popularly familiar, and a disease that, had it been studied under any but one particular phase, would have proved, of all others, the most instructive. There is no malady, under certain circumstances, more extensively fatal. In the Spanish conquest in America—a history scarcely less interesting in a medical than in a moral point of view—it seems that not all the cruelties of the Spaniards were more destructive than the small-pox. In less than a century after the arrival of Columbus, it was computed that it had destroyed more than half the population; and in one year (1590), it so spread along the coast of Peru, that it swept away nearly the whole of the Indians, the Mulattoes, and the Mestichos, in the cities of Potosi and De la Hay As is well known, before the discovery of vaccination, persons were inoculated with the small-pox, because it was found that the disease could be thus rendered comparatively harmless; whilst, if it was taken naturally, as it was termed, it was always serious, and too frequently extremely fatal. The preparation for inoculation consisted of measures addressed to the digestive organs. Now the effect may be judged of by this fact: Inoculation was at first violently opposed; and, in reply to the alleged safety of it, That such persons had, nevertheless, the genuine malady, was proved by the fact they were capable of infecting others (unprepared) with the disease in its most malignant form. But our notions of the mode in which the laws of the animal economy deal with injurious influences of this kind, are mischievously conventional. What quantities, for example, of mercury, in its different forms, have been administered in almost all diseases; and yet unquestionably there is a great deal of false reasoning in regard to this poison. Effects are attributed to it as mercury, which only belong to it in its general character of an injurious agent. All the (so-called) specific effects of it, most of which are become popularly familiar, may occur without any mercury at all. We have seen them induced by aloes, by scammony; and in a case where no medicine had been given, and where the only detectable poison was one which was to be sure bad enough, an enormously loaded liver. We are obliged to say but little here in connection with this subject. Abernethy's cases were very important in relation to the influence of the digestive organs, although he did not see the generalization to which, as it appears to us, they help to conduct the pathologist. The subject is too extensive for discussion here. We will attempt something of a popular view of it, when we endeavour to explain the fallacy to which we have already referred. Abernethy next adduces various illustrations from cases of other diseases; as indurations, tumours, carbuncles, scrofulous affections, and others; in proof of the dependence of a "numerous and dissimilar progeny" of so-called local diseases, on that "fruitful parent," disorder of the digestive organs. Of one of the most interesting and remarkable cases of tumour, Mr. Abernethy did not live to see the termination. It was of a lady who consulted him previous to the proposed infliction of an operation. She had been recommended by my father, in the country, to consult Abernethy before submitting to it; because he disapproved of it, as did Abernethy—not because they doubted of the nature The lady used to call on Abernethy when she came to town; and after his death she came to me—as she said, just to report her condition. She had at times various disturbances of her digestive organs; but always from some imprudence; for, although habitually very simple in her habits, she would be sometimes careless or forgetful. She died at a very advanced age—between seventy and eighty—but there had been no return of the disease for which she had originally consulted Abernethy, nor had she undergone any operation. It is a significant circumstance, too, that she had a sister who died of cancer. The whole of the cases are, however, scarcely less valuable. In the fifth section, he treats of disorders of parts having continuity of surface with the alimentary canal, certain affections of the nose, of the eye, and of the gullet or oesophagus. His observations on the latter are especially valuable. They strike at that meddling practice which is too common in the treatment of diseases of these parts. Many of us have recommended a practice which, without neglecting either, relies less on manipulatory proceedings, and more on measures directed to the general health, in such cases; as producing effects which are not to be obtained by other means; but, if we are to judge from the medical periodicals, without much success; so inveterate is the habit of imagining that, whatever the causes of disease may be, if the results be but mechanical, mechanical means can alone be applicable. Public attention, and the perusal of such cases as those of Abernethy, can alone correct these errors. Lastly, he describes the results of his dissections as bearing on the whole subject. Here he shows, that whilst disordered function may take place coincidentally with, or as a consequence of, change of structure, yet that such change, so as to afford visible or detectable departures from natural appearances, is by no means necessary, in organs which, during life, had afforded the most incontrovertible evidence of impaired function. He also shows that disease has terminated in disorder which had its original seat He speaks also suggestively of the possibility of that which is certainly now an established fact. He says: "In cases of diseased lungs, where no disease of the digestive organs is discovered, yet considerable disorder does exist, and may continue for many years without any organic disease being apparent; it is possible that such disorder may excite disease of the lungs, and thus produce a severer disease of the latter organs than what existed in the former. Accurate attention to the digestive organs may determine this important subject, and lead to the prevention and cure of the sympathetic diseases which I have mentioned." "This attention must not be merely of that general kind which adverts only to the quality of the ingesta, &c., but one which more strictly observes whether the viscera" (that is, reader, not merely the stomach, not merely the digestive organs, but the whole viscera of the body) "and whether these secretions are healthy or otherwise." After speaking of the heart also, as affected by the digestive organs; and of the infinity of diseases which arise from the reciprocal disturbance excited between them and the brain;—he says: "But even these are not the worst consequences. The disorder of the sensorium, excited and aggravated (by the means which he has described), affects the mind. The operations of the intellect become enfeebled, perplexed, and perverted; the temper and disposition, irritable, unbenevolent, and desponding. The moral character and conduct appears even to be liable to be affected by these circumstances. The individual in this case is not the only sufferer, but the evil extends to his connections and to society. The subject, therefore, appears to me to be of such importance, that Lastly, as if, notwithstanding his own previous attention to the important question of the influence of the digestive organs in disease, he felt that the inquiry had grown upon him in consequence of Mr. Boodle's endeavour to concentrate his attention to the subject, he concludes by expressing his past obligations to Mr. Boodle; for he says, with admirable modesty and candour, "for Mr. Boodle first instructed me how to detect disorders of the digestive organs, when their local symptoms were so trivial as to be unnoticed by the patient." He urges Mr. Boodle to publish also his own observations on the subject, because any remarks from one who observes the progress of disease "with such sagacity and accuracy, cannot but be interesting." We are quite aware how feeble our attempt has been to do justice to this admirable book. But nothing can do that but a careful study of the various principles which it either suggests, dimly shadows forth, or deeply and beautifully unfolds. Through not a very short life, we have had ample opportunity of testing these principles by the bedside, and of endeavouring to connect some of them with the laws in obedience to which they occur; and we are free to declare our impression that when the book is studied with the requisite previous knowledge, and freedom from preconceived opinion; and when tested and carried out in principle, as distinguished from any adhesion to mere matters of detail; we think it infinitely more valuable than all other professional works whatever. In examining the truths it unfolds, or in our humble endeavours elsewhere at a more analytical or extended application of them, like Abernethy, we have rested our reasoning wholly on facts and observations which are acknowledged and indisputable. Whilst other views have only led to a practice in the highest degree empirical, or, what is worse, conjectural, those of Abernethy's lead often directly, but always when duly studied, to a practice at once clear, definite, and in the sense in which we shall In order, however, to carry out this clearly, we shall at once add what we think necessary to the profession and the public on the subject. The general relation of Abernethy's labours to a real and definite science will be better developed in our concluding Summary; when we may have an opportunity of stating what further appears to have been done, and what is yet required. It will have been perhaps already observed that Abernethy's views involve a few very simple propositions: first, that disturbance of a part is competent to disturb the whole system; and conversely, that disturbance of the whole system is competent to disturb any part. That the disturbance may commence in the brain or nervous system, may then disturb the various organs, and that these may again by reflected action disturb the brain, and so reciprocally; and that in all these cases tranquillity of the digestive organs is of the very first consequence; not merely from its abstract importance, but from the influence it exerts on the state of the nervous system. With respect to any influences immediately directed to the nervous system, these we apprehend to be few and simple; some kinds of medicine, are, no doubt, in particular cases useful, none are susceptible of general application. None of them are certain; and sedatives of all kinds, which appear to have the most direct influence on the nervous system, either require to be employed with the utmost caution, or are in the highest degree objectionable. But there are other direct influences, certainly; and very important they are. Quiet, avoidance of disturbing external impressions, whether of light, sound, temperature, &c. whether in fact of mind or body; but, in the majority of mankind, how few of them we can, in a strictly philosophical sense, command. We are therefore driven to other sources of disturbance; and in the digestive organs we find those on which we can exert great influence, and in which tranquillity, however procured or under whatever circumstances, is certain, pro tanto, to relieve the whole To examine the question, we must for the moment forget our admiration of Abernethy; be no longer dazzled by his genius, but look only to our duty; endeavour to discover his defects, or rather those of the state of the question when he left us, and see what further investigation has afforded in aid of supplying them. In the first place, we must examine a little further that proposition which we have seen both in Hunter and Abernethy under different forms. Hunter says the disturbance of the organ sympathizing is sometimes more prominent than that of the organ with which it sympathizes. Abernethy says that the organ primarily affected is sometimes very little apparently disturbed, or not even perceptibly so. Now, from both these statements, we find that there may be no signs in the primarily affected organ; which, practically rendered, is nothing more or less than saying that in many cases we must not seek for the primarily affected organ where the symptoms are; and this is a great fact: because, although it does not necessarily teach us what we must do, it exposes the broken reed on which so many rely. Now the further point, which, as we would contend, time and labour have supplied, is first this—that what Hunter had mentioned as one feature in the history of the sympathies of different organs, and Abernethy as an occasional or not unfrequent occurrence, is, in disorders of any standing, and with the exception of mechanical injury, in fact the rule—the symptoms of disorder being almost never in the primary organ; nay, even organic change (disease) is for the most part first seen in a secondarily affected organ. In regard to primarily affected parts, the skin only excepted, they will be found, in the vast majority of cases, to be one or other of the digestive organs. I will endeavour to render the cause of this intelligible. A minute examination of what happens in a living person, especially if it be extended to some thousands of cases, will soon disclose to the most unlettered person a few instructive facts, showing that Nature has a regular plan of dealing with all injurious influences, which, however various many of the details may be, is in general character exquisitely simple, surprisingly beautiful, and intelligibly conservative; and that the various modes on which she exercises this plan, from the cradle to the grave, are, in frequency, directly in the order of their conservative tendency. Let us explain. There is no dearth of illustration; the facts are bewilderingly abundant; the difficulty is which to choose, and how to give them an intelligible general expression. Let us take a single case. We know that if a mote gets into the eye, there is irritation, immediately there is flow of blood to the part, a gland pours forth an abundant supply of tears, and the substance is probably washed out. Very well; we say that is intelligible. But suppose you have the vapour of turpentine, or any other irritant, the same thing happens; but still you cannot give quite the same mechanical explanation. Again—substances which affect the mouth, nose, and stomach, will irritate the eye without any contact, and cause a flow of tears. Lastly, you know that affections of the mind will do this, and where even we have no mechanical irritant at all. In all these cases there has been activity of the vessels of the eye, and in all it has been relieved by secretion. Now this is the universal mode throughout the body; all irritation of the organs is attended by secretion; and where this is done, there is no disorder; or rather, the disorder is relieved: but if organs are irritated continuously, another thing happens, and that is, that an organ becomes unable to secrete constantly more than is natural, and then some other organ, less irritated in the commencement, takes on an additional duty—that is, the duty of the animal economy is still done, but not equally distributed. This is the state in which most people are in crowded cities, and who live in the ordinary luxury or the ordinary habits of But of course there is a limit to this power in organs of taking on additional or compensating actions; and when this limit is exceeded, then those actions are instituted which we call Disease. The site is seldom found to be that of the original disturbance; and usually for a very plain reason—because there it would be more dangerous, or fatal. It would be scarcely less serious in many cases, even though placed on organs secondarily affected; and therefore it is more usually determined to the surface of the body; where, taking them simply in the order of their greatest number, or frequency, we find the first class of diseased appearances, and which strikingly impress the real nature of the law. They are the most numerous, most obviously dependent on general disturbance, and most conservative, as being least fatal. Diseases of the skin are those to which we allude, and which, in the characters I have mentioned, exceed all other diseases. Again—the next surface is that involution of the skin which covers the eye, and which lines the mouth, throat, and the whole of the interior surface of the respiratory tubes and the digestive organs. Here again we find the next seat of greatest frequency, and the conservative tendency, to coincide. We need only refer to the comparative frequency of what are called colds, ordinary sore throat, and so forth; as contrasted with those more serious diseases which occur in the corresponding surfaces of the respiratory organs and alimentary canal. In tracing diseases onwards in the order of their number, we never lose sight of this conservative tendency. When organs become involved in disease, we find that, for once that the substance of the organ is so affected, the membrane covering it is affected a hundred, perhaps a thousand times. This is equally observable with respect to the brain, heart, lungs, digestive organs, and some other parts; and it is of great importance practically to know how readily affections are Finally, then, we arrive at diseases of Organs; and here we see this conservative tendency still typed in the site first chosen, which is almost always (where we can distinguish the two structures) not so much in the actual tissue of the organ as in that which connects it together—what we term the cellular tissue. This is remarkable in the lungs; where tubercular deposits are first seated; not in the essential structures of the organs, but in those by which they are joined together. All those various depositions also which are called tumours, generally begin in, and are frequently confined to, the cellular tissue; and even though there is, in certain malignant forms of tumour, a disposition to locate themselves in organs, there is a very curious tendency towards such, as may have already fulfilled their purposes in the animal economy. We might multiply these illustrations to a tedious extent. We might show, for example, in the eye, how curiously the greatest number of diseases in that organ are placed in structures least dangerous to the organ; and even when the organ is spoiled, so to speak, how much more frequently this is in relation to its function as an optical instrument, than to the structure which forms the link with the brain, as an organ of sensation. I must, however, refer those who wish to see more of the subject, to the work To return to the bearing of all this on Abernethy's views, and In the same manner, the lungs and heart are continually disordered, and ultimately diseased, from causes which primarily act on the liver; and I have seen such a case treated with cod-liver oil and bitter ales, with a result which could not but be disastrous. The liver sends an enormous quantity of blood to the heart and lungs, from which it ought previously to have extracted a certain quantity of carbon (bile). If this be not done, the heart and lungs are oppressed both by the quantity and the quality of the blood sent to them. If nothing happen in either of the various sites I have mentioned, the blood must be got rid of; and it is so. In many cases, a vessel gives way; or blood is poured out from a vessel; or blood is employed in building up the structures of disease; but then the symptoms are frequently altogether in the chest, and not a sign of anything wrong in the liver. I cannot go on with the multitudinous illustrations of these principles. The law is to determine injurious influences to the surface. Deposition in the cellular tissue of the lung is bad enough; but it is better—that is, less certainly fatal—there, than in the respiratory tubes: and that is the explanation. But now comes the practical point. How is the primary organ to be got at? because that is the way to carry out the removal of the impediments to the sanative processes of nature, By going back to the former life of the patient, we shall seldom fail to discover the various influences to which he has been subjected, and the organs to which they have been originally addressed. Having made up our minds, from our previous knowledge of injurious influences, on what organ they will most probably have acted, we now test this, not merely by inquiry after symptoms—and it may be not by symptoms at all—but by careful observation of the actual work of the suspected organ. In this way we almost certainly discover the real offender; in other words, the organ primarily affected. This is of immense importance; for we confidently affirm that one single beneficial impression made on it will do more in a short time—nay, in some rare instances, in a single day—than years of routine treatment, that has been, nevertheless, of good general tendency. In treating it—i. e. the primary organ—however, great discrimination is necessary. If it be already organically affected, that treatment which would be, under other circumstances, necessary, becomes either objectionable, or requiring the utmost caution. For although an organ diseased in structure will, under some circumstances, as Abernethy long ago observed, yield its characteristic secretion, yet, unless we know the extent of the disease, which is just the thing we can almost never be certain about, excitement of it is never without danger. We should therefore excite the primary organ with more or less energy, with more or less caution, or not at all, according to circumstances. If we determine on not exciting it, we should then act on organs with which it has ordinarily closest community of function, or on whose integrity we can most depend. For choice, we prefer organs which, in a natural state, have nearest identity of function, as having the readiest sympathy, it may be, with each other. Yet so universal is the sympathy between all the organs, that there is no one that will not, under certain circumstances, or which may We must not here pursue this subject further. We have endeavoured to sketch certain extensions of the views of Mr. Abernethy, and can only refer the profession and the public, for the facts and arguments which demonstrate and illustrate them, to those works in which they have been enunciated SECTION. Mr. Abernethy's book "On the Constitutional Origin of Local Diseases" had an extensive circulation, and excited a great deal of attention from the public as well as the profession. As a work which may be read as it were in two days, so as a person read it with one or other subject, it produced a great variety of impressions. It may be read simply as a narrative of a number of facts, with the inferences immediately deducible from them. All this is plain and intelligible at once to anybody, and of great practical value; but the work contains numerous observations of a suggestive kind, which require careful thought, and some previous knowledge, to enable a person to estimate their value, or to trace their onward relations. The impression made by the work on different minds varied, of course, with the reader, his information, and, in some sort, with the spirit in which it was studied. Some, who had, in their solitary rides, and in the equally solitary responsibilities of country practice, been obliged to think for themselves, recognized, in the orderly statement of clearly enunciated views, facts and principles which they had already seen exemplified in their own experience, and hailed with admiration and pleasure a book which realized their own ideas, and supplied a rational explanation of their truth and value. Some, who had never thought much on the subject, and were very ill-disposed to begin, regarded his ideas as exaggerated, and hastily dismissed the subjects, with the conclusion that he was a clever man, but too full of theory, and too much disposed to look to the stomach or the digestive organs. Others, making very little distinction between what they heard of the man, the book, or his practice, and probably not having seen either, but deriving only a kind of dreamy notion of a clever man with many peculiarities, would say that he was mad, or an enthusiast. Still, a great many of the thinking portion of the public and the profession held a different tone. The book was recognized as an intelligible enunciation of definite views—rather a new thing in medical science. The application of them became more and more general; his pupils were everywhere disseminating them, more or less, in the navy, in the army, in the provinces, and in America. Still, it must not be imagined that his principles became diffused with that rapidity which might have been inferred from his numerous and attentive class. Constituted as medical education is, but more especially as it was at that time—for it is slowly improving—pupils However various, too, the impressions made by his book, there are two things certain; viz. that he was much talked of, and the book had an extensive sale, went through several editions, and served to give the public some notion of those principles which he was so beautifully unfolding to the younger portions of the profession in his lectures. Besides, although there were not wanting those who spoke disparagingly of him, still, as an old and very far-seeing colleague of our own used to say, with perhaps too much truth, when canvassing the various difficulties of a medical man's progress in the metropolis, "A man had better Abernethy had now an amount of practice to which neither he nor any other man could do full justice. Finding it impossible to make people understand his views in the time usually allotted for consultation, he now referred his patients to his book, and especially page 72. This has been made the subject of a great deal of quizzing, and of something besides, not altogether quite so good-natured. For our parts, we think it the most natural thing in the world to refer a patient to a book, which may contain more in full the principles we desire them to understand, than we can hope to find opportunity to explain at the time of consultation. We think that if asking a few questions, and writing a prescription (and we are here only thinking of a reasonably fair average time visit), be worth a guinea, the explaining a principle, or so placing a plan before a patient that his following it may be assisted and secured, is worth fifty times as much; and it came particularly well from Abernethy, one of whose lessons, and a most excellent lesson too, was the remark, "That if a medical man thought he had done his duty when he had written a prescription, and a patient regarded his as fulfilled when he had swallowed it, they were both deceived." As we are convinced that, cÆteris paribus, success in medical treatment is indefinitely promoted by both patient and surgeon clearly understanding each other as to principles, we think it would be of great use if every medical man, who has any definite principles of practice, were to explain them in short printed digests. Nay, we have sometimes thought it would be useful to both parties, if, in addition to the inquiries and advice given at consultation, a medical man should have brief printed digests of the general nature and relations of most of the well-defined diseases. A careful perusal of one of these would help the patients to comprehend the nature and objects of the advice given, tend to the diffusion of At this time, whilst, with a considerable indifference to money, he was making a large income, still he was obliged to work hard for it. He had as yet no emolument from the Hospital; he was still only an assistant surgeon. The tenacity of office, of which assistant surgeons so commonly complain, they have themselves seldom failed to exercise when they have become surgeons (Mr. Abernethy, however, excepted). The long tenure of office by his senior (Sir James Earle) wearied him, and was at times a source of not very agreeable discussions. On one occasion, Sir James was reported to have given Abernethy to understand that, on the occurrence of a certain event, on which he would obtain an accession of property, he, Sir James, would certainly resign the surgeoncy of the hospital. About the time that the event occurred, he happened one day to call on Abernethy, and was reminded of what he had been understood to have promised. Sir James, however, having, we suppose, a different impression of the facts, denied ever having given such a pledge. The affirmative and negative were more than once exchanged, and not in the most courteous manner. When Sir James was going to take his leave, Abernethy opened the door for him, and, as he had always something quaint or humorous to close a conversation with, he said, at parting, "Well, Sir James, it comes to this: you say that you did not promise to resign the surgeoncy of the hospital; I, on the contrary, affirm that you did: now all I have to add is, —— the liar!" In 1813, Abernethy accepted the surgeoncy of Christ's Hospital, In 1814, he was appointed Professor of Anatomy and Surgery to the College of Surgeons—an appointment which could be, at this period, of little service to him, whatever lustre it might reflect on the College, where he gave lectures with a result which has not always followed on that appointment: namely, of still adding to his reputation. He was one of the few who addressed the elders of the profession without impressing the conviction that he had been too much employed in addressing pupils. He had given lectures two years in succession, when, in 1816, circumstances occurred which will occupy us for some little time. A new scene will be opening upon us; and this suggests the period (1815–16) as convenient for taking a retrospect, and a sort of general view of Abernethy's position. |