From William Summers the disease was transfered to William Pead a boy of eight years old, who was inoculated March 28th. On the 6th day he complained of pain in the axilla, and on the 7th was affected with the common symptoms of a patient sickening with the Small-pox from inoculation, which did not terminate 'till the 3d day after the seizure. So perfect was the similarity to the variolous fever that I was induced to examine the skin, conceiving there might have been some eruptions, but none appeared. The efflorescent blush around the part punctured in the boy's arm was so truly characteristic of that which appears on variolous inoculation, that I have given a representation of it. The drawing was made when the pustule was beginning to die away, and the areola retiring from the centre. (See Plate, No. 3.) Plate 3