Although the preceding history pretty clearly evinces that the constitution is far less susceptible of the contagion of the Cow Pox after it has felt that of the Small Pox, and although in general, as I have observed, they who have had the Small Pox, and are employed in milking cows which are infected with the Cow Pox, either escape the disorder, or have sores on the hands without feeling any general indisposition, yet the animal economy is subject to some variation in this respect, which the following relation will point out:

In the summer of the year 1796 the Cow Pox appeared at the Farm of Mr. Andrews, a considerable dairy adjoining to the town of Berkeley. It was communicated, as in the preceding instance, by an infected cow purchased at a fair in the neighbourhood. The family consisted of the Farmer, his wife, two sons, a man and a maid servant; all of whom, except the Farmer (who was fearful of the consequences), bore a part in milking the cows. The whole of them, exclusive of the man servant, had regularly gone through the Small Pox; but in this case no one who milked the cows escaped the contagion. All of them had sores upon their hands, and some degree of general indisposition, preceded by pains and tumours in the axillÆ: but there was no comparison in the severity of the disease as it was felt by the servant man, who had escaped the Small Pox, and by those of the family who had not, for, while he was confined to his bed, they were able, without much inconvenience, to follow their ordinary business.

February the 13th, 1797, I availed myself of an opportunity of inoculating William Rodway, the servant man above alluded to. Variolous matter was inserted into both his arms; in the right by means of superficial incisions, and into the left by slight punctures into the cutis. Both were perceptibly inflamed on the third day. After this the inflammation about the punctures soon died away, but a small appearance of erysipelas was manifest about the edges of the incisions till the eighth day, when a little uneasiness was felt for the space of half an hour in the right axilla. The inflammation then hastily disappeared without producing the most distant mark of affection of the system.