SARAH PORTLOCK, of this place, was infected with the Cow Pox, when a Servant at a Farmer's in the neighbourhood, twenty-seven years ago[1].

In the year 1792, conceiving herself, from this circumstance, secure from the infection of the Small Pox, she nursed one of her own children who had accidentally caught the disease, but no indisposition ensued.–During the time she remained in the infected room, variolous matter was inserted into both her arms, but without any further effect than in the preceding case.

1: I have purposely selected several cases in which the disease had appeared at a very distant period previous to the experiments made with variolous matter, to shew that the change produced in the constitution is not affected by time.