CONTENTS

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Introduction 11
CHAPTER I
Its History and Its Extension 19
History of Plague—The Widespread Dissemination of Plague in Recent Years—The Appearance of Plague in Porto Rico, New Orleans and Manila.
CHAPTER II
The Cause and the Menace of Plague 28
Causation of the Disease and its Mode of Conveyance—Types of Plague—Chronic Plague and Immunity in Rats—Flea Conveyance of Plague Bacilli—The Stability of Virulence of Plague Bacilli—Summary of Facts Concerning the Cause and Manner of Extension of Plague.
CHAPTER III
Its Control and Suppression 40
Plague Prevention by Extermination of Rats—General Uselessness of the Rat and Its Enormous Destructiveness, with Details of Trapping and Other Extermination Methods—The Manila Epidemic, 1912–1914—The First Cases—Unusual Character of Plague Cases at Quarantine—Clinical Description of Two Cases at Quarantine—Inauguration of the Manila Epidemic—Directed to Take Charge of Plague Suppression in Manila—Plague Fighting Organization—Method of Rat Proofing and Rat Destruction—Correspondence Between Dr. Jackson and Dr. Heiser, Director of Public Health—Observations on Fleas and Their Habits—Conditions of Habitations in Manila Favoring Rat Multiplication and Spread of Plague—Comparative Statistics on Methods of Catching Rats—The Natural Enemies of the Flea—ZoÖlogic Classification of Rats—A Collection of Notes Concerning Rat Runs, Rat Nests, Multiple House Infections and Other Data—Sample of Detailed Orders Issued Regarding Rat Extermination—Method of Procedure of Collecting and Forwarding Rats Suspected of Plague Infection to Laboratory—Memoranda in Plague Cases—Letter of Warning and Appeal for CoÖperation—Bacteriologic Observations made During the Manila Plague Epidemic, by Dr. Otto SchÖbl—Notes Concerning the Bubonic Plague in Hong Kong, by Dr. David Roberg.
CHAPTER IV
Its Diagnosis and Treatment 165
Biologic Diagnosis—Necessity for Trained Bacteriologist—Bacteriologic Procedure—Non-Biologic Diagnosis—Symptomatology—Pathologic Considerations—Treatment, Conditions and Prognosis—Serum Treatment—Symptomatic Treatment—Statistical Studies in Mortality—Dosage and Technique of Serum Administration—Prophylactic Serum and Anaphylaxis—Plague Vaccines.

                                                                                                                                                                                                                                                                                                           

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