Ralph Sheldon, who was born on the 1st of August 1623, at Beoley in Worcestershire, was the eldest son of William Sheldon of Beoley and Elizabeth, daughter of William, second Lord Petre. He was privately educated, and at the age of nineteen he paid a visit to France and Italy, and resided at Rome for some time, returning home about 1647, after an absence of four years from his native country. Sheldon appears to have been greatly respected, and Nash, in his Collections for the History of Worcestershire, says 'he was a person of such rare worth and excellent qualities as deserve particular notice. He was a great patron of learning and learned men, and well skilled in the history and antiquities of his country, sparing no money to set up a standing library at Weston. He was a great friend to Anthony Wood, and left him a legacy of £40. He purchased the valuable MSS. of the ingenious Augustine Vincent, Windsor Herald, and Keeper of the records in the Tower, temp. Charles I., which at his death he bequeathed to the Heralds' College, where they are still preserved; and allowed John Vincent his son a yearly pension for many years. He travelled often to Rome, and spent some time there to furnish himself with choice books, coins and medals. In short, he was of such remarkable integrity, charity and hospitality, as gained him the universal esteem of all the gentlemen of the county; insomuch that he usually went by the name of the Great Sheldon.... And for the sufferings which himself and father had undergone in the civil wars, he was nominated by Charles II. one of the gentlemen of Warwickshire, who were to have received the honour of the Order of the Royal Oak, had it been instituted; his estate being then valued at £2000 per annum, the largest of any in the county, except that of the Middlemores of Edgbaston, which was estimated of the same annual value.' The library formed by Sheldon at his manor-house of Weston in the parish of Long Compton, Warwickshire, was a fine one. Among the printed books was a very curious and probably unique copy of the first folio of Shakespeare (now the property of the Baroness Burdett-Coutts), where the concluding passages of Romeo and Juliet, and the opening passages of Troilus and Cressida, are printed twice over at different parts of the volume. This irregularity was discovered by Mr. Sidney Lee, who read a paper on the subject before the Bibliographical Society on March 21, 1898. The library at Weston was dispersed in 1781.

In commemoration of Sheldon's gifts to Heralds' College, Mr. Ralph Bigland, who was created Blue Mantle in 1757, and died as Garter in 1784, caused a handsome canvas to be painted, on which are emblazoned Sheldon's arms, impaled with those of his wife, accompanied by the following biographical notice:—'To the Memory of Ralph Sheldon of Beoley in the County of Worcester, Esquire, a great Benefactor to this Office. Who died at his Manor-House of Weston in the Parish of Long-Compton, in the County of Warwick, on Midsu[~m]er Day, 1684, aged 61 years wanting 6 weeks: the Day afterwards his Heart and Bowels were buried in Long-Compton Chancel, in a Vault by those of his Father, Mother, Grandfather, etc., and on the 10th of July following, his Body in a Vault by his Ancestors under our Lady's Chapel, Joyning on the North Side to St. Leonard's Church of Beoley: He married Henrietta-Maria, Daughter of Thomas Savage, Viscount Rock-Savage by Elizabeth his wife, Daughter of Thomas, Lord Darcy, of Chich in Essex, Viscount Colchester and Earl Rivers, but by her had no issue.'

This canvas is still preserved in Heralds' College.

Sheldon compiled A Catalogue of the Nobility of England since the Norman Conquest, according to theire severall Creations by every particular King, with the arms handsomely emblazoned. This manuscript came into the possession of Sir Thomas Phillipps, and formed one of the lots at the sale of his collection in June 1893.